Bariatric Surgery and Male Reproductive Function

Effect and Mechanism of Bariatric Surgery on Male Reproductive Function

Obesity is a global public health problem. According to literature reports, as of 2016, China's obese population has reached more than 90 million and type 2 diabetes mellitus has reached more than 100 million, which has brought a serious health and economic burden to China. In addition to various health problems such as cardiovascular, osteoarthritis, and tumors, obesity can also cause abnormalities in reproductive endocrine. In women, it can cause abnormal menstruation, polycystic ovary syndrome, and male obesity can cause secondary gonadal. Hypofunction (MOSH). MOSH is an endocrine dysfunction. It is reported to have a prevalence of approximately 45% in moderate to severe obesity. In addition, studies have pointed out that the prevalence of hypogonadism in men with type 2 diabetes and obesity higher. However, there are no studies on the reproductive function of Chinese male patients after bariatric surgery. Pre- and post-operative semen will be collected for analysis to observe the effect of bariatric surgery on male reproductive function.

Inclusion Criteria:

• Meet the surgical indications according to the Chinese Guidelines for Surgical Treatment of Obesity and Type 2 Diabetes (2019 Edition).
• 20 years old< patient<60 years old.
• Male

Exclusion Criteria:

• Incapacity of giving an informed consent.
• Drug and / or alcohol abuse.
• Scrotal injury and previous scrotal surgery.
• Use of phosphodiesterase-5 inhibitors.
• Mental illnesses that may affect compliance with clinical research, including dementia, active psychosis, major depression, or attempted suicide.