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There is association between eye movement disorder and cognitive dysfunction. Therefore, utilizing eye movement and screening for cognitive dysfunction is feasible. In the present study, the investigators will develop an artificial intelligence platform to screening for cognitive dysfunction by inspecting the function of eye movement. Futher more, based on the screening results, the platform will offer referral suggestions.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Normal | Subjects over 45 years old without cognitive dysfunction | ||
| Mild cognitive decline | Subjects who are diagnosed as mild cognitive decline(MCI) according to neurologists. | ||
| Alzheimer's disease | Subjects who are diagnosed as Alzheimer's disease(AD) according to neurologists. | ||
| Vascular dementia | Subjects who are diagnosed as vascular dementia(VD) according to neurologists. | ||
| Lewy body dementia | Subjects who are diagnosed as Lewy body demenita (DLB) according to neurologists. | ||
| Frontotemporal dementia | Subjects who are diagnosed as Frontotemporal demenita (FD) according to neurologists. | ||
| Other dementia | Subjects who are diagnosed as dementia but are not as AD, VD, DLB OR FD. |
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| Measure | Description | Time Frame |
|---|---|---|
| Area under the curve | AUC values for predicting whether subject has cognitive impairment or not | up to 1 month |
| Measure | Description | Time Frame |
|---|---|---|
| Accuracy, true positive rate, and true negetive rate | The performance of this artificial platform | up to 1 month |
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Inclusion Criteria:
Exclusion Criteria:
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Subjects who are over 45 years old with or without cognitive dysfunction.
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| Name | Affiliation | Role |
|---|---|---|
| Haotian Lin, M.D.,Ph.D | Zhongshan Ophthalmic Center, Sun Yat-sen University | Study Chair |
| Xun Wang, M.D.,Ph.D | Zhongshan Ophthalmic Center, Sun Yat-sen University | Study Director |
| Shuyi Zhang, M.D. | Zhongshan Ophthalmic Center, Sun Yat-sen University | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Zhongshan Ophthalmic Center | Guangzhou | Guangdong | 510060 | China |
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| ID | Term |
|---|---|
| D015835 | Ocular Motility Disorders |
| D060825 | Cognitive Dysfunction |
| ID | Term |
|---|---|
| D002493 | Central Nervous System Diseases |
| D009422 | Nervous System Diseases |
| D003389 | Cranial Nerve Diseases |
| D005128 | Eye Diseases |
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| D003072 | Cognition Disorders |
| D019965 | Neurocognitive Disorders |
| D001523 | Mental Disorders |