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Alveolar bone regeneration after laser-assisted extraction will be compared with bone regeneration after standard extraction procedure.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Laser | Experimental | After extraction, Er:YAG and Nd:YAG lasers used for degranulation, disinfection, deepithelialization, clot stabilization and photobiomodulation. |
|
| Control | Active Comparator | Standard extraction procedure. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Er:YAG and Nd:YAG lasers | Device | Extraction followed by Er:YAG laser degranulation, Nd:YAG laser disinfection, Er:YAG deepithelialization, Nd:YAG blood clot stabilization and photobiomodulation. The photobiomodulation step repeated on day 3, 5, and 7. |
| Measure | Description | Time Frame |
|---|---|---|
| Change in bone density from immediate post-extraction | Cone Beam Computed Tomography (CBCT) | 3 months |
| Measure | Description | Time Frame |
|---|---|---|
| Bone density | Cone Beam Computed Tomography (CBCT) | 3 months |
| Bone thickness | Cone Beam Computed Tomography (CBCT) | 3 months |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Aleksandra Križaj Dumić, MDD | Krizaj d.o.o. | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Klinika Križaj | Ljubljana | 1000 | Slovenia |
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Patients will be randomly assigned to either laser or control group.
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CBCT will be used to assess bone density and the assessors will be unaware of the patient allocation.
|
| Standard extraction | Procedure | Standard extraction procedure |
|
| Treatment pain | On a pain scale from 0 (no pain) to 10 (intolerable pain) | day 1 |
| Treatment pain | On a pain scale from 0 (no pain) to 10 (intolerable pain) | day 3 |
| Treatment pain | On a pain scale from 0 (no pain) to 10 (intolerable pain) | day 5 |
| Treatment pain | On a pain scale from 0 (no pain) to 10 (intolerable pain) | day 7 |