A Study on the Effect of Platelet Rich Plasma (PRP) on Osteoarthritis in the Thumb Base

A Study on the Effect of Platelet Rich Plasma (PRP) on Osteoarthritis in the Thumb Base

Randomized comparison between Platelet Rich Plasma (PRP) and placebo (Saline) for thumb base.osteoarthritis.

Inclusion Criteria:

• Arthritis in the thumb base.
• Radiological Eaton Littler class 1-3.
• Clinical signs of thumb base osteoarthritis: pain at palpation of the CMC-1 joint and pain during provocation/grinding test.

Exclusion Criteria:

• Rheumatoid arthritis.
• Ongoing infection in the hand or wrist.
• History of gout or pseudo gout.
• Inability to co-operate with the follow-up protocol (language difficulties, severe psychiatric disorder, cognitive impairment, drug addiction).
• Intra-articular injection in the affected joint within 6 months.
• Eaton Littler class 4 (STT joint involved).