Single Blinded First CMC Osteoarthritis Treatment

Randomized Single Blinded First CMC Osteoarthritis Treatment: Therapy and Bracing Alone vs. Intra-Articular Corticosteroid Injection vs Intra-Articular Leukocyte Depleted Platelet Rich Plasma

Single blinded PRP vs. Corticosteroid vs. Placebo (normal saline) intra-articular injection for basal joint arthritis.

Inclusion Criteria:

• Stage 1-3 osteoarthritis of the basal joint

Exclusion Criteria:

• Patients with Stage 4 1st carpometacarpal joint arthritis as described by Eaton
• Patients who have received a corticosteroid injection in the last year to the 1st CMC joint on the proposed study side
• Patients who have scaphotriquetral, radioscaphoid, or scaphotrapezial osteoarthritis
• Patients who have concurrent DeQuervain's tenosynovitis or intersection syndrome or have been treated for either of these in the last 3 months
• Patients undergoing evaluation of cervical radiculopathy
• Patients with fibromyalgia or inflammatory rheumatic disease
• Patients with Pressier disease, Kienbock's, or avascular necrosis of the scaphoid
• Patients with any history of primary or secondary bone tumor
• Patients that are pregnant or terminally ill