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Hypertension is the most common chronic diseases and a most important risk factor for cardiovascular and cerebrovascular diseases, and also a substantial public health problem. The purpose of the study is to investigate the association between biomarkers and adverse outcomes in patients with hypertension.
Study population includes subjects who are hypertension, of any race or ethnicity, 18 or older years of age, and have provided written informed consent to provide whole blood specimens at one or more study visits.
Physical examination, questionnaire survey and biological sample collection will be conducted at baseline and the incidence of all-cause and cardiovascular mortality will be investigated during follow-up.
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Non-interventional study | Other | This is an observational, non-interventional study |
| Measure | Description | Time Frame |
|---|---|---|
| All-Cause Mortality | All-cause mortality was confirmed through a combination of hospital medical records, telephone contacts with patients or family members, and death registration at the Guangdong Provincial Center for Disease Control and Prevention. | From date of inclusion until the date of death from any cause, assessed up to 1 year |
| Measure | Description | Time Frame |
|---|---|---|
| Cardiovascular Mortality | Cardiovascular mortality was defined as death attributable to an ischemic cardiovascular cause (including fatal MI, stroke). | From date of inclusion until the date of death from any cause, assessed up to 1 year |
| Measure | Description | Time Frame |
|---|---|---|
| Secondary outcomes of cardiovascular diseases | The number of and the incidence rate of cardiovascular diseases. | Through study completion, an average of 1 years |
| Secondary outcomes of cerebrovascular diseases |
Inclusion Criteria:
Exclusion Criteria:
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Patients with hypertension
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Feng Ying-qing, PhD | Contact | 86-2083827812 | 651792209@qq.com | |
| HUANG Yu qing, MD | Contact | +8613172054256 | hyq513@126.com |
| Name | Affiliation | Role |
|---|---|---|
| Feng Ying-qing, PhD | Guangdong Provincial People's Hospital | Study Director |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Guangdong Provincial People's Hospital | Recruiting | Guangzhou | Guangdong | 510080 | China |
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| ID | Term |
|---|---|
| D006973 | Hypertension |
| D002318 | Cardiovascular Diseases |
| ID | Term |
|---|---|
| D014652 | Vascular Diseases |
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This study will collect 20 mL whole blood samples from subjects at one or more study visits. The whole blood will be processed to plasma and stored for testing
The incidence rate of cerebrovascular diseases.
| Through study completion, an average of 1 years |
| Secondary outcomes of kidney | The incidence rate of hypertensive renal injure and end-stage renal disease | Through study completion, an average of 1 years |
| others | Number of participants with reported hospitalization due to other diseases(eg. diabetes， tumor) | From date of inclusion until the date of first event, assessed up to 1 year |
| Guangdong Cardiovascular Institute | Recruiting | Guangzhou | Guangdong | 510100 | China |
|