Detection of Subclinical Enthesitis by Ultrasonography

Detection of Subclinical Enthesitis by Ultrasonography in Psoriasis Patients With Psoriasis and Controls: by Ultrasonography; Incidence of Psoriatic Arthritis During Within One 1 Year

Detection of subclinical enthesitis by ultrasonography

A total of 30 patients with psoriasis and 30 age-matched healthy controls, all without musculoskeletal diseases, will be recruited. They will undergo dermatological assessment and a blinded ultrasound (US) evaluation. Clinical assessment included demographics, severity of psoriasis and musculoskeletal clinical examination. Evaluation consisted of the detection of grey scale (GS) enthesitis and Power Doppler signal in enthesis areas. The Madrid Sonography Enthesitis Index (MASEI) scoring system was used to quantify the extent of sonographic entheseal abnormalities.

Inclusion Criteria:

• Age≥18years
• Patients with psoriasis without musculoskeletal symptoms
• Healthy controls
• No joint involvement and no clinical symptoms and signs of enthesitis and synovitis

Exclusion Criteria:

• Have history of gout or arthritis or peripheral neurological disease of lower extremity.
• Have history of trauma and intensive sport activity in last 2 weeks.
• Have received any systemic therapy (i.e. DMARD, NSAIDs, corticosteroids, immunosuppressants, retinoids or biological agents) in 3 months
• Pregnant or breast-feeding