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| Name | Class |
|---|---|
| University of Reading | OTHER |
| The Scientific and Technological Research Council of Turkey | OTHER |
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Studies have shown that the effect of fat mass and obesity-associated (FTO) gene on obesity is modulated by lifestyle factors. Hence, we aimed to determine whether two single nucleotide polymorphisms (SNPs) in the FTO gene are associated with obesity and to assess whether these associations were modified by lifestyle factors. The study included 200 obese and 200 non-obese individuals from Turkey. Our study suggests that the effect of the SNPs on obesity traits is likely to be influenced by lifestyle factors in this Turkish population.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| study | obese (BMI ≥25.00 kg/m2, n=200) | ||
| control | non-obese (BMI= 18.50-24.99 kg/m2, n=200) |
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| Measure | Description | Time Frame |
|---|---|---|
| Genetic analysis of two SNPs at FTO gene | FTO SNPs rs9939609 and rs10163409 | up to 36 weeks |
| Anthropometric measurements | Body mass index, waist circumference, hip circumference, body composition | up to 36 weeks |
| Biochemical measurements | lipid profile, glucose, insulin, adiponectin | up to 36 weeks |
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Inclusion Criteria:
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400 unrelated individuals, aged 24-50 years
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| Name | Affiliation | Role |
|---|---|---|
| Zehra Buyuktuncer | Hacettepe University, Department of Nutrition and Dietetics, Ankara, TURKEY | Principal Investigator |
| Vimales Karani Santhanakrishnan | Department of Food and Nutritional Sciences, University of Reading, UK | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Zehra Buyuktuncer | Ankara | 06100 | Turkey (Türkiye) |
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| ID | Term |
|---|---|
| D009765 | Obesity |
| D005247 | Feeding Behavior |
| D020022 | Genetic Predisposition to Disease |
| ID | Term |
|---|---|
| D050177 | Overweight |
| D044343 | Overnutrition |
| D009748 | Nutrition Disorders |
| D009750 | Nutritional and Metabolic Diseases |
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| D001835 |
| Body Weight |
| D012816 | Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |
| D001522 | Behavior, Animal |
| D001519 | Behavior |
| D004198 | Disease Susceptibility |
| D020969 | Disease Attributes |
| D010335 | Pathologic Processes |