Evaluation in Healthy Volunteers of CARDIOSPACE II

Evaluation in Healthy Volunteers of CARDIOSPACE II for Physiological Studies in Space

The aim of this project is to test the CARDIOSPACE II system that integrates several medical devices. This system is dedicated to physiological studies in space environment.

• Electrocardiogram
• Vascular doppler
• Laser doppler with iontophoresis
• Continuous blood pressure recording at the finger level
• Brachial blood pressure
• Ultrasound
• Ambulatory Electrocardiogram and SAO2 (arterial oxygen saturation) recorder

Inclusion Criteria:

• Height between 160 et 180 cm
• Body mass index between 18 et 24
• Normal blood pressure, heart rate and cardio-pulmonary auscultation at rest
• Normal electrocardiogram
• Possibility to perform transcranial doppler
• Able to understand aims and constraints of this study
• National health insurance
• Signature of the informed consent form

Exclusion Criteria:

• Pregnant woman (Beta HCG - human chorionic gonadotropin - with urinary test) or breastfeeding
• Participating at the time to another clinical trial investigating
• Reached or surpassed the annual amount of financial compensation allowed by clinical trials (according to French regulation)
• Taking any chronic treatment
• Any sign of cardiovascular or respiration disease
• Any sign of syncopal events by questioning (>2 events per year)
• Contraindication to perform physical activity