Comparison of Volume Assist Control, Dual Mode and Airway Pressure Release Ventilation.

Comparison of Volume Assist Control, Dual Mode and Airway Pressure Release Ventilation: A Physiological Study

The aim of the COMIX-R study is to assess the short term physiological effects of 3 ventilation strategies for adult patients with ARDS admitted to intensive care unit

Inclusion Criteria:

• 18 years or older
• Invasive mechanical ventilation on tracheal probe
• Acute respiratory distress syndrome, as defined by Berlin conference consensus, during hospitalization in intensive care,
• Recovery phase of acute respiratory distress syndrome: spontaneous ventilation representing from 20 to 30% of ventilation in APRV mode.
• No severe acidosis (pH> 7.30)
• Patient affiliated to or beneficiary of a health care plan
• Express consent of the patient or his/her SDM

Exclusion Criteria:

• Pneumothorax
• Contraindication to the insertion of a nasogastric tube with an esophageal balloon
• Contraindication to the use of Electrical impedance tomography (pacemaker)
• Pregnancy, lactating or parturient woman