Interactions of Brain Regions in Visuomotor Adaptation

Functional Interaction of Thalamus, Basal Ganglia, and the Cerebellum in Visuomotor Adaptation

The purpose of this study is to better understand the roles the cerebellum, basal ganglia, and thalamus play in motor learning. Patients undergoing High Intensity Focused Ultrasound (HIFU) treatment will be receiving an ablation procedure to their thalamus as a part of their medical procedure. Participation in this study will include completing a behavioral task before and after the procedure to see how motor learning task performance differs with and without the thalamus. Similarly, patients undergoing Deep Brain Stimulation (DBS) treatment will have an electrode implanted in their thalamus as a part of their medical procedures. Participation in this study will include completing the motor learning task performance "on" and "off" thalamic electrical stimulation.

Inclusion Criteria:

• Be a patient receiving either high intensity focused ultrasound treatment or deep brain stimulation treatment for Tremor
• Able to provide informed consent and complete study procedures
• Must speak English
• Age 18-85

Exclusion Criteria:

• Not receiving one of the specified inclusion criteria
• Unable to provide consent or complete study procedures
• Women who self-report pregnancy
• Patients who are currently incarcerated