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The purpose of this study is to better understand the roles the cerebellum, basal ganglia, and thalamus play in motor learning. Patients undergoing High Intensity Focused Ultrasound (HIFU) treatment will be receiving an ablation procedure to their thalamus as a part of their medical procedure. Participation in this study will include completing a behavioral task before and after the procedure to see how motor learning task performance differs with and without the thalamus. Similarly, patients undergoing Deep Brain Stimulation (DBS) treatment will have an electrode implanted in their thalamus as a part of their medical procedures. Participation in this study will include completing the motor learning task performance "on" and "off" thalamic electrical stimulation.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| High Intensity Focused Ultrasound | Experimental | Patients receiving high intensity focused ultrasound as a treatment will be asked to complete the behavioral task pre and post their treatment. |
|
| Deep Brain Stimulation | Experimental | Patients receiving deep brain stimulation as a treatment will be asked to complete the behavioral task while their DBS electrode is "on" and "off". |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Behavioral Assessment | Behavioral | Patients will be asked to complete the behavioral assessment before and after their HIFU treatment or "on" and "off" their DBS treatment. |
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| Measure | Description | Time Frame |
|---|---|---|
| Performance Error on Visuomotor Task | The visuomotor task has practice, baseline, and experimental trials. Performance on the task will be compared between groups (HIFU treatment and DBS treatment) before and after treatment. | baseline, a week after HIFU treatment, several weeks after DBS implantation |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Sarah Adams | Contact | 4342434319 | neuromodlab@hscmail.mcc.virginia.edu |
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| University of Virginia | Recruiting | Charlottesville | Virginia | 22903 | United States |
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| ID | Term |
|---|---|
| D009483 | Neuropsychological Tests |
| ID | Term |
|---|---|
| D011581 | Psychological Tests |
| D004191 | Behavioral Disciplines and Activities |
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