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Cranial USG is simple and easy method to assess preterm infant brain. Some studies showed that brain volumes of preterm infants could be calculated by measurement of 2D distances. Our aim in this study was to compare brain volume obtained by USG and MRI.
All preterm infants less than 32 weeks of gestational age undergo cranial USG examination routinely at least, in the first week of life, at the end of first month and corrected age 36 weeks and 40 weeks. We will performa all USG mesurements with measureing intracranial hegiht, anteroposterior diameter, biparietal diamater, ventriccular height, thalamo-occipital distance and ventricular index. We will calculate the brain volume as a spheric geometric shape than we will calculate two ventricles as conical shapes. Absolute brain volume will be calculating by substracting two ventricles from total brain volume. At 40 weeks of age we will perform a cranial MRI to show exact brain volume and we will ccompare two different methods.
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Cranial MRI | Other | Cranial MRI |
| Measure | Description | Time Frame |
|---|---|---|
| Results of two different brain volumes | Patients in cohort will have both USG and cranial MRI | 6 months |
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Inclusion Criteria:
Exclusion Criteria:
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Preterm infants under 32 weeks of GA and 800-1200 gram BW all admitted to Ankara Şehir Hospital MH5 NICU
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| FUAT EMRE CANPOLAT, MD | Contact | 05055668716 | femrecan@gmail.com |
| Name | Affiliation | Role |
|---|---|---|
| Mustafa Şenol Akın, MD | Ankara City Hospital Bilkent | Study Chair |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Ankara City Hospital | Recruiting | Ankara | Turkey (Türkiye) |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 27783429 | Background | Benavente-Fernandez I, Lubian-Gutierrez M, Jimenez-Gomez G, Lechuga-Sancho AM, Lubian-Lopez SP; Neonatal Neurology Foundation (Fundacion Nene). Ultrasound lineal measurements predict ventricular volume in posthaemorrhagic ventricular dilatation in preterm infants. Acta Paediatr. 2017 Feb;106(2):211-217. doi: 10.1111/apa.13645. Epub 2016 Nov 21. | |
| 27174146 |
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| Cheong JL, Thompson DK, Spittle AJ, Potter CR, Walsh JM, Burnett AC, Lee KJ, Chen J, Beare R, Matthews LG, Hunt RW, Anderson PJ, Doyle LW. Brain Volumes at Term-Equivalent Age Are Associated with 2-Year Neurodevelopment in Moderate and Late Preterm Children. J Pediatr. 2016 Jul;174:91-97.e1. doi: 10.1016/j.jpeds.2016.04.002. Epub 2016 May 9. |