Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
The main aim of this study is to examine the effect of olive oil consumption on several cardiovascular risk markers between Caucasians and Asian ethnicity. The primary assessments: endothelial function's biomarkers: cell and vascular adhesion molecules (ICAMs and VCAMs) and nitric oxide (NO). The secondary assessments: Lipid profile.
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Olive oil | Experimental | Participants will receive 30ml/day of olive oil for two weeks |
|
| Butter | Placebo Comparator | Participants will receive 30g/day of butter also for two weeks. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Olive oil | Dietary Supplement | Participants will be randomly allocated to receive daily dose of 30ml of olive oil (OO) as intervention group or a matching control (butter 30g) for 2 weeks each (i.e. two weeks olive oil and two weeks butter), separated by a washout period of 2 weeks between treatments. |
| Measure | Description | Time Frame |
|---|---|---|
| changes in ambulatory blood pressure | Baseline and 2 weeks |
| Measure | Description | Time Frame |
|---|---|---|
| Changes in plasma total cholesterol | Plasma total cholesterol vascular cell adhesion molecule 1 | Baseline and 2 weeks |
| Changes in Intercellular Adhesion Molecule 1 | Plasma levels of Intercellular Adhesion Molecule 1 measured |
Not provided
Inclusion Criteria:
Male
Orient Asians (including Chinese, Japanese, Korean, and Malaysia Chinese) and Caucasians
Age 18-70 years
Self-reported in good general health
Exclusion Criteria:
Female
Age older than 70 years or younger than 18 years
Diagnosed and/or are taking medications for hypertension (>140/90mmHg)
Diabetes
High blood cholesterol
Heart problems (e.g. arrhythmia, high-grade stenosis of the carotid artery or carotid sinus syndrome)
Allergy to olive oil or olive oil products
Lactose intolerance
Taking omega-3 supplements in fish oil and vitamins supplements in the last six months.
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Department of Applied Sciences, Faculty of Health and Life Sciences, Northumbria University | Newcastle upon Tyne | NE1 8ST | United Kingdom |
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| ID | Term |
|---|---|
| D000069463 | Olive Oil |
| D002079 | Butter |
| ID | Term |
|---|---|
| D004042 | Dietary Fats, Unsaturated |
| D004041 | Dietary Fats |
| D005223 | Fats |
| D008055 | Lipids |
Not provided
Not provided
A randomized, double-blind, placebo-controlled crossover trial.
Not provided
Not provided
Not provided
Not provided
|
| Butter | Dietary Supplement | Participants will be randomly allocated to receive daily dose of 30ml of olive oil (OO) as intervention group or a matching control (butter 30g) for 2 weeks each (i.e. two weeks olive oil and two weeks butter), separated by a washout period of 2 weeks between treatments. |
|
| Baseline and 2 weeks |
| Changes in vascular cell adhesion molecule 1 | Plasma levels of vascular cell adhesion molecule 1 measured | Baseline and 2 weeks |
| Changes in C-reactive protein | Plasma levels of CRP measured | Baseline and 2 weeks |
| D005224 |
| Fats, Unsaturated |
| D010938 | Plant Oils |
| D009821 | Oils |
| D005502 | Food |
| D000066888 | Diet, Food, and Nutrition |
| D010829 | Physiological Phenomena |
| D019602 | Food and Beverages |
| D003611 | Dairy Products |