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This study was a retrospective observational cohort analysis of subjects aged 65 years and older, who underwent bilateral cataract surgery within a single (15 hospital) healthcare system, to determine the association between type (conventional or blue-light filtering) of implanted intraocular lens and survival.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Blue-light filtering intraocular lens (IOL) | Bilateral implantation of blue-filtering intraocular lens. Blue-IOL, in addition to ultraviolet, also impede the transmission of the lower visible blue spectrum between 400 and 500nm. |
| |
| Conventional intraocular lens (IOL) | Bilateral implantation of conventional ultraviolet light-blocking intraocular lens |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Blue-light filtering intraocular lens | Device | Bilateral implantation of blue light-blocking intraocular lens |
|
| Measure | Description | Time Frame |
|---|---|---|
| All-cause mortality | The primary outcome was all-cause mortality. Mortality was identified based on the Social Security Death Master File and discharge status. Follow-up started from the day after the initial surgery until the end of the study period or death, whichever occurred first. Time to death was calculated as the number of days from the first cataract surgery to death. Participants who did not have a recorded death were censored on April 30, 2019. | From the date of the initial cataract surgery until the date of death or end of the study period (April 30, 2019), whichever occurred first, assessed up to 2,310 days. |
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Inclusion Criteria:
Exclusion Criteria:
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The study population consisted of all adult patients (at least 65 years) who underwent bilateral cataract surgery between January 01, 2012 and January 01, 2018 within the University of Pittsburgh Medical Center (UPMC) healthcare system.
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| Name | Affiliation | Role |
|---|---|---|
| Matthew R Rosengart, MD MPH | University of Pittsburgh | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| UPMC-Presbyterian Hospital | Pittsburgh | Pennsylvania | 15213 | United States |
Individual participant data that underlie the results reported in this article, after de-identification (text, tables, figures, and appendices) will be shared.
Beginning12 months and ending 36 months after publication.
Data will be shared with researchers who provide a methodologically sound proposal.
Analyses are limited to those to achieve the aims listed in the approval proposal.
Proposals should be directed to mrr18@pitt.edu; to gain access, data requestors will need to sign a data access agreement.
Information regarding accessing data may be obtained after approval of the proposal.
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| ID | Term |
|---|---|
| D002386 | Cataract |
| D021081 | Chronobiology Disorders |
| D005901 | Glaucoma |
| D008268 | Macular Degeneration |
| ID | Term |
|---|---|
| D007905 | Lens Diseases |
| D005128 | Eye Diseases |
| D009422 | Nervous System Diseases |
| D009798 | Ocular Hypertension |
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| Conventional intraocular lens | Device | Bilateral implantation of conventional intraocular lens |
|
| D012162 |
| Retinal Degeneration |
| D012164 | Retinal Diseases |