The Effect of a Blue Light Filtering IOL

The Effect of a Blue Light Filtering Intraocular Lens on Blood Retinal Barrier After Cataract Surgery

To compare the effect on blood retinal barrier disruption 3 and 12 months after implantation of either a blue light filtering intraocular lens(blue-filtering IOL) or an ultraviolet light filtering intraocular lens(UV-filtering IOL).

The following parameters were measured for evaluation of blood retinal barrier disruption.

• the incidence of macular leakage by fluorescence angiography (FA)
• the mean fluorescein concentration in the vitreous by fluorophotometry (VFP)
• the thickness of the macula by optical coherence tomography (OCT)

Results

• the incidence fo macular leakage decreased significantly from 24%(3 months) to 5% (12 months) in the blue-filtering IOL group (P<0.05), and was significantly lower compared with the UV-filtering IOL group at 12 months.
• the VFP significantly decreased in both group from 3 to 12 months.
• the OCT decreased from 175 (3 months) to 166 um (12 months) in the blue- filtering IOL group.

Inclusion Criteria:

• cataract patients
• All eligible for intraocular lens implantation

Exclusion Criteria:

• Patients had undergone an intraocular operation
• Patients had hypertensive retinopathy
• Patients had diabetic retinopathy
• Patients had ange-related macular degeneration
• no observable fundus
• The cataract operation was more than 30 minutes in duration