Oral Use of Dexketoprofen/Tramadol for Acute Postoperative Pain in Total Hip Replacement With a Direct Anterior Approach.

EVALUATION OF ORAL USE OF DEXKETOPROFEN/TRAMADOL IN ACUTE POSTOPERATIVE PAIN IN PATIENTS UNDERGOING TOTAL HIP REPLACEMENT WITH A MINIMALLY INVASIVE ANTERIOR APPROACH (AMIS).

Pain is a global public health issue and represents the most common reason for both physician consultation and hospital admissions . When unrelieved or poorly controlled, it is associated with medical complications, poor patient satisfaction and increased risk of developing chronic pain. Dexketoprofen is a new NSAID treating acute postoperative pain and when it combined with tramadol may have a better effect. The purpose of this study is to evaluate the analgesic effect of the oral use of the combination of dexketoprofen/tramadole on the reduction of postoperative pain after total hip arthroplasty with minimal invasive anterior approach (AMIS).

Inclusion Criteria:

• unilateral total hip arthroplasty with a direct anterior minimal invasive technique
• ASA score I or II
• signed written informed consent form
• 3 days hospitalization
• 45-80 years old
• primary Total hip arthroplasty

Exclusion Criteria:

• allergy to any given drugs
• contraindications for spinal anesthesia
• active bleeding
• renal failure ( gfr< 90ml/h)
• hepatic failure ( abnormal sgot,sgpt,γgt)
• heart failure
• history of gastrointestinal bleeding