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To determine the cognitive and neurophysiological dose-response relationships of anodal tDCS to the left DLPFC as a function of absolute current intensity, individualized E-field intensity, and stimulation duration.
To determine the cognitive and neurophysiological dose-response relationships of anodal tDCS to the left DLPFC as a function of absolute current intensity, individualized E-field intensity, and stimulation duration.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| ADHD | Other | Patients with ADHD. |
|
| Healthy Control | Other | Volunteers without Neuropsychiatric Disorders. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Transcranial Direct Current Stimulation | Device | In tDCS, electrodes are applied on the scalp to transmit direct current at low current amplitudes. |
|
| Measure | Description | Time Frame |
|---|---|---|
| Change in Accuracy and Reaction Time in Attention and Working Memory | Measured using Eriksen Flanker Task (EFT) | Change Before and After Stimulation on Each of the Four Visits, Average of 2-6 Weeks |
| Measure | Description | Time Frame |
|---|---|---|
| Amplitude of Electroencephalogram (EEG) Event Related Potentials | Measure of amplitude related to stimulus | Change Before and After Stimulation on Each of the Four Visits, Average of 2-6 Weeks |
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Inclusion Criteria (Patients)
Exclusion Criteria (Patients)
Inclusion Criteria (Healthy Control)
1. Male and female outpatients 18-55 years of age
Exclusion Criteria (Healthy Control)
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| Name | Affiliation | Role |
|---|---|---|
| Joan Camprodon, MD, PhD, MPH | Massachusetts General Hospital | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Massachusetts General Hospital | Boston | Massachusetts | 02129 | United States |
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| ID | Term |
|---|---|
| D001289 | Attention Deficit Disorder with Hyperactivity |
| ID | Term |
|---|---|
| D019958 | Attention Deficit and Disruptive Behavior Disorders |
| D065886 | Neurodevelopmental Disorders |
| D001523 | Mental Disorders |
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| ID | Term |
|---|---|
| D065908 | Transcranial Direct Current Stimulation |
| ID | Term |
|---|---|
| D004599 | Electric Stimulation Therapy |
| D013812 | Therapeutics |
| D003295 | Convulsive Therapy |
| D013000 | Psychiatric Somatic Therapies |
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| D004191 | Behavioral Disciplines and Activities |
| D004597 | Electroshock |
| D011580 | Psychological Techniques |