Analgetic Effect of Two Solutions of Intracameral Anesthesia During Cataract Surgery in Patients

Comparison of Analgetic Effect of Two Solutions of Intracameral Anesthesia During Cataract Surgery: a Pilot Study

Purpose: The aim of the study was to compare the analgetic effect of two solutions of intracameral anesthesia in patients undergoing cataract surgery and assess the factors influencing the patients' postoperative activities.

Methods: In this prospective, single-blind, randomized study, a group of 62 patients undergoing cataract surgery received Mydrane (Mydrane group) or a combination of 1% solution of lignocaine and 0.025% solution of adrenalin (reference group) as an intraocular anesthetic. The analgetic effect of these two anesthetic methods was evaluated using psychological tools - Visual Analog Scale for Pain (VAS Pain) and Brief Pain Inventory-short form (BPI) on the next day after the surgery.

Inclusion Criteria:

• age above 18 years
• best corrected visual acuity (BCVA) of 0.2 logMAR or worse
• and agreement for taking part in the study

Exclusion Criteria:

• depressive disorder or expected compliance problems (known psychiatric disease)
• epilepsy
• ongoing treatment with hypnotics or psychotropic drugs (including opioids) within a week before admission
• daily analgesic treatment
• intake of additional rescue medications due to the pain after surgery
• omitting postoperative visit
• no consent to complete the survey
• The patients who later needed additional medications for pain relief