Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Name | Class |
|---|---|
| Seoul National University Bundang Hospital | OTHER |
Not provided
Not provided
Not provided
Not provided
The investigator measured the arterial stiffness using cardio-ankle vascular index (CAVI) test in patient with preeclampsia and normal pregnant women to evaluate the longitudinal change of CAVI and their predictors.
This study was a case control study and included 37 women with preeclampsia (PE group) and 36 normotensive women (control group) who gave birth to child at Seoul National University Bundang Hospital.
Cario-ankle vasuclar index (CAVI) was measured at one day, six months and one year after delivery in both group.
The investigator also checked the body weight, blood pressure, lipid profile, serum creatinine, aspartate transaminase (AST) and alanine transaminase (ALT) simultaneously with CAVI.
The relationship between the presence of preelampsia and longitudinal changes of CAVI, blood pressure and metabolic indices were evaluated using generalized estimating equation (GEE) method.
Not provided
Not provided
Not provided
Not provided
| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Preeclampsia group | PE was defined as diastolic BP of at least 110 mmHg on one occasion or diastolic BP of at least 90 mmHg on two consecutive occasions more than 4 hours apart, in combination with proteinuria (≥300 mg total protein in a 24-hour urine collection and, if this was not available, ≥+2 proteinuria by dipstick analysis on two consecutive occasions at least 4 hours apart) that develops after 20 weeks of gestation in previously normotensive women | ||
| Control group | Normal pregnancy group |
Not provided
| Measure | Description | Time Frame |
|---|---|---|
| The differences in longitudinal change pattern of CAVI between preeclampsia and normal pregnant women. | The CAVI was analyzed with generalized estimating equation (GEE) method to evaluate the different change pattern of CAVI between two groups. | The CAVI was measured at one day, six months and one year after delivery in both groups. |
| Measure | Description | Time Frame |
|---|---|---|
| Systolic blood pressure | automated blood pressure, mmHg | one day, six months and one year after delivery |
| Diastolic blood pressure | automated blood pressure, mmHg |
Not provided
Inclusion Criteria:
Exclusion Criteria:
Not provided
Not provided
This study included 37 women with preeclampsia (PE group) and 36 normotensive women (control group) who gave birth to child at Seoul National University Bundang Hospital from March 2013 to May 2016.
Not provided
| Name | Affiliation | Role |
|---|---|---|
| Jung-Won Suh, MD, PhD | Seoul National University Bundang Hospital | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Seoul National University Bundang Hospital | Seongnam-si | Gyeonggi-do | 463707 | South Korea |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 33176736 | Derived | Kim S, Lim HJ, Kim JR, Oh KJ, Hong JS, Suh JW. Longitudinal change in arterial stiffness after delivery in women with preeclampsia and normotension: a prospective cohort study. BMC Pregnancy Childbirth. 2020 Nov 11;20(1):685. doi: 10.1186/s12884-020-03374-0. |
Not provided
Not provided
Not provided
| ID | Term |
|---|---|
| D011225 | Pre-Eclampsia |
| D004461 | Eclampsia |
| ID | Term |
|---|---|
| D046110 | Hypertension, Pregnancy-Induced |
| D011248 | Pregnancy Complications |
| D005261 | Female Urogenital Diseases and Pregnancy Complications |
| D000091642 | Urogenital Diseases |
Not provided
Not provided
Not provided
Not provided
Not provided
| one day, six months and one year after delivery |
| Body weight | kilograms | one day, six months and one year after delivery |
| Waist/Hip ratio | Waist circumference in centimeter, Hip circumference in centimeter, Waist/Hip Circumference Ratio is the ratio of waist circumference divided by hip circumference | one day, six months and one year after delivery |
| Lipid profiles (Total cholesterol, TG, LDL, HDL) | mg/dL (milligrams per deciliter) | one day, six months and one year after delivery |
| AST(aspartate aminotransferase), ALT(alanine aminotransferase) | IU/L (International Units Per Litre) | one day, six months and one year after delivery |
| Serum creatinine | mg/dL (milligrams per deciliter) | one day, six months and one year after delivery |