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Achieving the optimal sedation level for patient management is not always possible using our standard intravenous medications in Pre-hospital Emergency medicine. Inhaled sedation is possible with the Anesthetic-conserving device with a standard respirator.
The pharmacodynamics and pharmacokinetics of halogenated agents allow deep sedation quickly after absorption.
The feasibility of inhaled sedation has never been studied in hospital.
Retrospecive clinical monocentric study with sedated ventilated patients with isoflurane with the AnaConda® system out of hospital.
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| Measure | Description | Time Frame |
|---|---|---|
| depth of sedation | depth of sedation (measured by the Ramsay Score) 10 minutes from start of the sedation and at stop of pre hospital sedation. The Ramsay score ranges level of sedation from 1(patient anxious ,agitated,restless) to 6 (patient exhibits no response). | up to 1 day |
| Measure | Description | Time Frame |
|---|---|---|
| hemodynamic tolerance of patients during isoflurane sedation | comparison of heart rate (heart beats per minute) before isoflurane start and 10 minutes from start of the sedation and at stop of pre hospital sedation | up to 1 day |
| hemodynamic tolerance of patients during isoflurane sedation |
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Inclusion Criteria:
Exclusion Criteria:
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patients who were sedated by isoflurane with Anesthetic-conserving device in pre-hospital by the emergency teams of SAMU 29
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| CHRU de Brest | Brest | 29609 | France |
All collected data that underlie result in a publication
Data will be available beginning three months and ending five years following the publication
Data access requests will be rewiewed by internal committee of Brest UH. Requestors will be required to sign and complete a data access agreement.
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comparison of medium blood pressure (mmHg) before isoflurane start and 10 minutes from start of the sedation and at stop of pre hospital sedation |
| up to 1day |