Differential Expression and Analysis of Peripheral Plasma Exosome miRNA in Patients With Myocardial Infarction

Differential Expression and Analysis of Peripheral Plasma Exosome miRNA in Patients With Myocardial Infarction

The aim of this study is to determine the miRNA expression profile in peripheral blood exosomes of patients with myocardial infarction and to investigate its relationship with myocardial infarction.

Collect exosomes in peripheral blood of patients with myocardial infarction, compare the expression of miRNA with healthy volunteers, find out the miRNAs with significant differences, and explore its relationship with the development of myocardial infarction.

Inclusion Criteria:

• Age > 18 years ST elevation by ECG diagnostic of STEMI Evidency of coronary occlusion in coronariography Signed informed consent

Exclusion Criteria:

• Patients who will undergo immediate PCI Pregnant and lactating women Patients with mental disorders Patients are using other experimental drugs; Refusal to provide informed.