VDR and TFIP11 Gene Polymorphism and Gene-environmental Interaction in Adults

Association Between Enamel Gene Variants and Dental Caries in Adults

VDR and TFIP11 Gene polymorphism and gene-environment interactions on caries etiology and susceptibility in adults.

To date, genes can be grouped into categories based on the factor influencing dental caries. The major candidate gene categories to date include enamel formation genes, immune response genes, genes related to saliva, and genes related to taste and dietary habits.

TFIP11 and VDR genes are related to enamel formation genes

Inclusion Criteria:

• adult be between 24 and 40 years old
• subject has DMFT (Decayed, Missing, Filled, Permanent Tooth) DMFT≤4 , or, DMFT>13.9

Exclusion Criteria:

• systemic or genetic disorders
• orthodontic appliances
• pregnant women