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In this experiment, patients with chronic pure tone tinnitus were divided into three groups to receive auditory stimulation, somatosensory stimulation, vestibular stimulation and combined stimulation, in order to find an effective way to treat tinnitus
120 patients with chronic pure tone tinnitus over 6 months were randomly divided into 6 groups, one group was given auditory stimulation, one group was given somatosensory stimulation, one group was given auditory stimulation + somatosensory stimulation, one group was given auditory stimulation + vestibular stimulation, the last group was given auditory stimulation + somatosensory stimulation + vestibular stimulation.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| acoustic stimulation | Experimental | Pink noise in both ears is given to tinnitus patients. The pink noise is removed by notch filter from tinnitus frequencies that are 20 decibel higher than the threshold. |
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| somatic stimulation | Experimental | Three stimulation points were selected for each ear of tinnitus patients, namely ear door (CN.V), auditory Palace (CN.VII) and Yifeng (C2/3). The stimulation intensity should be needle-sensed. |
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| vestibular stimulation | Experimental | The patient sat on a rotating chair with sinusoidal harmonic acceleration and rotated without causing the greatest frequency of discomfort. |
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| acoustic + somatic stimulation | Experimental | Combination of auditory and somatic stimulation for tinnitus patients |
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| acoustic + vestibular stimulation | Experimental | Combination of auditory and vestibular stimulation for tinnitus patients |
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| multiple sensory stimulation | Device | The patients were recruited to record their medical history, and the hearing level, tinnitus indicators, vestibular function and tinnitus disability indicators were tested. Then the patients were randomly divided into six groups. They received the corresponding stimulation 20 minutes a day, 5 days a week for 3 weeks. After the last stimulation, the above tests were repeated immediately, one week later and three months later. |
| Measure | Description | Time Frame |
|---|---|---|
| Electrical audiometry and acoustic impedance | Assessment of hearing in patients | Three months from the time the patient was selected to the end of the stimulus |
| Tinnitus frequency and loudness | Detection of tinnitus frequency and loudness in patients | Three months from the time the patient was selected to the end of the stimulus |
| Tinnitus disability scale | Tinnitus handicap inventory score was used to detect the degree of tinnitus.0-16 points without disability, 18-36 points with mild disability, 38-56 points with moderate disability and 58-100 points with severe disability. The 95% confidence interval is 20 points, that is, the difference between the two tests before and after the experiment is greater than or equal to 20 points. | Three months from the time the patient was selected to the end of the stimulus |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Dan Su, master | Contact | +8615755149100 | sudan19966991@outlook.com | |
| Busheng Tong, doctor | Contact | +8613956040273 | 2871638103@qq.com |
| Name | Affiliation | Role |
|---|---|---|
| Busheng Tong, doctor | E.N.T. department of the First Affiliated hospital of Anhui Medical University | Study Director |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| E.N.T. department of the First Affiliated hospital of Anhui Medical University | Hefei | Anhui | 230000 | China |
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| ID | Term |
|---|---|
| D014012 | Tinnitus |
| ID | Term |
|---|---|
| D006311 | Hearing Disorders |
| D004427 | Ear Diseases |
| D010038 | Otorhinolaryngologic Diseases |
| D012678 | Sensation Disorders |
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| acoustic + somatic + vestibular stimulation | Experimental | Combination of auditory stimulation, somatic stimulation and vestibular stimulation for tinnitus patients |
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| D009461 |
| Neurologic Manifestations |
| D009422 | Nervous System Diseases |
| D012816 | Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |