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Differential diagnoses of MVNT include DNT (dysembryoplastic neuroepithelial tumor), low-grade gliomas, cortical dysplasias or even hamartomas.
Differential diagnoses of MVNT include DNT (dysembryoplastic neuroepithelial tumor), low-grade gliomas, cortical dysplasias or even hamartomas.
However, in order to avoid an invasive surgical procedure to remove the lesion, a certain diagnosis of its benignity is essential. The contribution of advanced techniques in MRI, such as spectroscopy in the characterization of these lesions, has not yet been studied today
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| cerebral MRI | Device | Patients who agree to participate in the study will perform a 3T multi-parametric MRI with advanced spectroscopic imaging techniques and standard protocol. A neurological consultation will take place during the inclusion visit as well as a questionnaire and a control MRI at 1 year and 2 years +/- 1 month. |
| Measure | Description | Time Frame |
|---|---|---|
| Description of a new radiological entity on Spectroscopy : the MVNT (Multinodular and Vacuolating Neuronal Tumor) | ratio of N-Acetylaspartate / Choline on Spectroscopy | 1 day |
| Description of a new radiological entity on Spectroscopy : the MVNT (Multinodular and Vacuolating Neuronal Tumor) | area under curve of the N-Acetylaspartate Spectroscopie | 1 day |
| Description of a new radiological entity on Spectroscopy : : the MVNT (Multinodular and Vacuolating Neuronal Tumor) | area under curve of choline Spectroscopie | 1 day |
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Inclusion Criteria:
Major criteria:
Minor criteria:
Absence of mass effect
Hyposignal T1
Center of the lesion in hypsignal FLAIR or T1 hypersignal
Exclusion Criteria:
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Patient supported for suspicion of MVNT
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Groupe Hospitalier Pellegrin | Bordeaux | Bordeaux | 33076 | France | ||
| Fondation Adolphe de Rothschild |
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| Paris |
| PARIS |
| 75019 |
| France |
| CHU Rennes | Rennes | Rennes | 35033 | France |
| CHU de Rouen | Rouen | Rouen | 76000 | France |
| Hôpital Pierre Paul Riquet, CHU Purpan | Toulouse | Toulouse | 31059 | France |
| Centre Hospitalier Lyon Sud | Pierre-Bénite | 69495 | France |
| Hôpital Laennec | Saint-Herblain | 44800 | France |