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This study evaluates the efficacy of visual perceptual learning for the treatment of visual field defect caused by brain damage. Half of participants will receive visual perceptual training using the Nunap Vision, while the other half will receive sham training using the Nunap Vision-C.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Nunap Vision | Experimental | Nunap Vision , 5 days a week for 12 weeks |
|
| Nunap Vision-C | Sham Comparator | Nunap Vision-C, 5 days a week for 12 weeks |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Nunap Vision | Device | Participants receive visual perceptual training using the Nunap Vision software |
|
| Measure | Description | Time Frame |
|---|---|---|
| Area of Humphrey visual field where sensitivity increased by equal or more than 6 dB relative to baseline | Improved regions have luminance sensitivity that increased by equal or more than 6 dB relative to baseline. The improved area ranges between 0 and 972 degree^2, of which larger area indicates better outcome. | 12 weeks |
| Measure | Description | Time Frame |
|---|---|---|
| Changes in Humphrey visual field mean deviation relative to baseline | Changes in mean deviation value of whole field or defect field compared with the baseline value. The change of mean deviation ranges between -35 to +35 dB, of which higher value indicates better outcome. | 12 weeks |
| Changes in scores of NEI-VFQ-25(the National Eye Institute Visual Function Questionnaire 25) relative to baseline |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Sun U. Kwon, MD, PhD | Asan Medical Center | Study Chair |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Seoul National University Bundang Hospital | Seongnam-si | Gyeonggi-do | South Korea | |||
| Asan Medical Center |
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| ID | Term |
|---|---|
| D006423 | Hemianopsia |
| ID | Term |
|---|---|
| D014786 | Vision Disorders |
| D012678 | Sensation Disorders |
| D009461 | Neurologic Manifestations |
| D009422 | Nervous System Diseases |
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| Nunap Vision-C | Device | Participants receive sham training using the Nunap Vision-C software |
|
Changes in each components of NEI-VFQ-25 scores relative to baseline. The change of scores ranges between -100 to 100, of which higher value indicates better outcome. |
| 12 weeks |
| Seoul |
| South Korea |
| Chung-Ang University Hospital | Seoul | South Korea |
| Konkuk University Hospital | Seoul | South Korea |
| Samsung Medical Center | Seoul | South Korea |
| D001766 |
| Blindness |
| D005128 | Eye Diseases |
| D012816 | Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |