Mycoprotein and Muscle Protein Synthetic Response | NCT04084652

Studies
Mycoprotein and Muscle Protein Synthetic Response

NCT04084652

Sponsor

University of Exeter

Status

Completed

Last Update Posted

May 27, 2022Actual

Enrollment

24Actual

Phase

Not Applicable

Conditions

Anabolic Response to Mycoprotein and Micronutrient Ingeston

Interventions

Mycoprotein ingestion

Countries

United Kingdom

Protocol Section

Identification Module Status Module Sponsor/Collaborators Module Oversight Module Description Module Conditions Module Design Module Arms/Interventions Module Outcomes Module Eligibility Module Contacts/Locations Module References Module IPD Sharing Statement Module

Results Section

Participant Flow Module Baseline Characteristics Module Outcome Measures Module Adverse Events Module More Info Module

Annotation Section

Annotation Module

Document Section

Large Document Module

Derived Section

Miscellaneous Info Module Condition Browse Module Intervention Browse Module

Protocol Section

Identification Module

NCT ID

Results Section

No data available

No data is available for this block.

Annotation Section

No data available

No data is available for this block.

Document Section

No data available

No data is available for this block.

Derived Section

Miscellaneous Info Module

Version Holder

Status Module

Record Verification Date

May 2022

Overall Recruitment Status or Expanded Access Status

Completed

Last Known Status

Not provided

Delayed Posting

Not provided

Why Stopped

Not provided

Expanded Access Info

Start Date

Apr 15, 2019Actual

Primary Completion Date

Dec 11, 2019Actual

Completion Date

Dec 11, 2019Actual

First Submitted Date

Sep 6, 2019

First Submission Date that Met QC Criteria

Sep 9, 2019

First Posted Date

Sep 10, 2019Actual

Results Waived

Not provided

Results First Submitted Date

Not provided

Results First Submitted that Met QC Criteria

Not provided

Results First Posted Date

Not provided

Certification/Extension (aka Delayed Results) First Submitted Date

Not provided

Certification/Extension First Submitted that Passed QC Review

Not provided

Certification/Extension First Posted Date

Not provided

Last Update Submitted Date

May 26, 2022

Last Update Posted Date

May 27, 2022Actual

Name	Class
Quorn	INDUSTRY

Oversight Module

Has Data Monitoring Committee (DMC)

Not provided

Is FDA Regulated Drug

Is FDA Regulated Device

Is Unapproved Device

Not provided

Pediatric Postmarket Surveillance of a Device Product

Not provided

Product Exported from US

Not provided

FDAAA801 Violation

Not provided

Description Module

Brief Summary

Dietary protein is vital for the preservation of health and optimal adaptation to training. However, traditional animal proteins come with a number of economic, environmental, and ethical issues. Accordingly, there is a need to develop an understanding of the utility of more sustainable non-animal derived dietary proteins to support our nutrition. Mycoprotein, produced by Quorn Foods™, has recently been shown to stimulate a greater anabolic response within skeletal muscle compared with milk protein, suggesting its utility within sports nutrition. However, it is unclear what accounted for the greater anabolic response of mycoprotein. One explanation could be the non-protein nutrients contained within mycoprotein (e.g. fibre, carbohydrate, fat or micronutrients).

Therefore, the present study will compare the muscle anabolic response between mycoprotein (MYC) as a whole food and the protein isolated from mycoprotein (PIM).

Detailed Description

Not provided

Design Module

Study Type

Interventional

Number of References to an Expanded Access Study

Not provided

Expanded Access Types

Not provided

Patient Registry

Not provided

Target Follow-Up Duration

Not provided

Phases

Not Applicable

Interventional Study Design

Allocation

Biospecimen

No data available

No data is available for this block.

Enrollment

24Actual

Arms/Interventions Module

Arm Groups

Label	Type	Description	Intervention Names
Mycoprotein	Experimental	Mycoprotein in its full food matrix	Dietary Supplement: Mycoprotein ingestion
Protein Isolated from Mycoprotein	Experimental	Protein from mycoprotein isolated from the food matrix	Dietary Supplement: Mycoprotein ingestion

Interventions

Name	Type	Description	Arm Group Labels	Other Names
Mycoprotein ingestion	Dietary Supplement	The ingestion of mycoprotein	Mycoprotein Protein Isolated from Mycoprotein

Outcomes Module

Primary Outcomes

Measure	Description	Time Frame
Muscle protein synthesis	The rate of synthesis of new muscle protein (Fractional Synthetic Rate %/h)	7.5 hours

Secondary Outcomes

Measure	Description	Time Frame
Plasma Amino Acid Kinetics	The rate of appearance of amino acids ingested in the drink	7.5 hours
Blood Glucose	The levels of glucose in the blood

Other Outcomes

Not provided

Eligibility Module

Eligibility Criteria

Inclusion Criteria:

BMI between 18 and 30.
Resistance trained

Exclusion Criteria:

Any metabolic impairments.
Cardio/pulmonary diseases.
Chronic use of over the counter pharmaceuticals
A personal or family history of epilepsy, seizures or schizophrenia.
Allergic to mycoprotein/Quorn/edible fungi/environmental mould products.

Accepts Healthy Volunteers

Yes

Sex

Male

Sex/Gender Based

Not provided

Sex/Gender Description

Not provided

Minimum Age

18 Years

Maximum Age

40 Years

Standard Ages

Adult

Study Population

Not provided

Sampling Method

Not provided

Contacts/Locations Module

Central Contacts

Not provided

Overall Officials

Not provided

Locations

Facility	Status	City	State	ZIP	Country	Contacts
University of Exeter		Exeter			United Kingdom

IPD Sharing Statement Module

Plan to Share IPD

Description

Not provided

Types

Not provided

Time Frame

Not provided

Access Criteria

Not provided

URL

Not provided