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No study coordinator available. No patient recruitment possible.
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The degree at which cataract surgery improves visual function in patients with advanced age-related macular degeneration (Advanced AMD) has been an on-going topic of discussion. Our objective in this study is to determine if patients with Advanced AMD and concurrent cataracts will experience greater improvement in their quality of life from having cataract surgery on one or both eyes. The findings from this project will provide evidence for clinical decision making on whether performing bilateral cataract surgery on Advanced AMD patients is cost-effective and worth the second surgical intervention.
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Cataract Surgery | Procedure | Patients with bilateral Advanced Age-related macular degeneration and concurrent cataracts will be receiving bilateral cataract surgery |
| Measure | Description | Time Frame |
|---|---|---|
| Life style Questionnaire to determine change in visual function. | Our primary outcome will be a life style questionnaire (qualitative) to determine the change in visual function from baseline to after surgery. This questionnaire includes 25 close-ended questions that are graded on a 5 point grading scale from 1 (great difficulty due to vision) and 5 (no problem due to vision). The questions can also be graded as not applicable to an individuals life, or 0 being something there are no longer possible to do, due to vision. The 25 close-ended questions are divided into 4 sub-scales:
A total score can range from a 125 indicating best visual function to 0 indicating complete loss of visual function. | Through study completion, an average of 1 year |
| Measure | Description | Time Frame |
|---|---|---|
| Snellens Chart to determine change in visual acuity | Quantitative measure of a patients visual acuity. Change from baseline visual acuity to after surgery on both eyes. | Through study completion, an average of 1 year |
| Auto Refractive to determine change in visual acuity |
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Inclusion Criteria:
Patients above the age of fifty with both Advanced AMD and Cataracts bilaterally from the Okanagan Valley will be selected for this study.
Patients who chose to have bilateral cataract surgery, were able to understand the research parameters, and had no other severe eye disease that may distort the studies results.
Patients will be selected for the study according to the National Eye Institute definition of Advanced AMD.
"Advanced AMD (AREDS category 4) is characterized by one or more of the following (in the absence of other causes) in one eye:
Geographic atrophy of the RPE involving the foveal center.
Neovascular maculopathy that includes the following:
Exclusion Criteria:
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| ID | Term |
|---|---|
| D002386 | Cataract |
| ID | Term |
|---|---|
| D007905 | Lens Diseases |
| D005128 | Eye Diseases |
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| ID | Term |
|---|---|
| D002387 | Cataract Extraction |
| ID | Term |
|---|---|
| D054140 | Refractive Surgical Procedures |
| D013508 | Ophthalmologic Surgical Procedures |
| D013514 | Surgical Procedures, Operative |
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An auto-refractor is a computerized machine to measure patients visual acuity. Change from baseline visual acuity to after surgery on both eyes. |
| Through study completion, an average of 1 year |