Study of Hypoxia Measured in F-Miso PET/Scan and MRI in Patients With Squamous Cells Carcinoma

Comparative Study of Hypoxia Measured in F-Miso PET/Scan and MRI in Patients With Squamous Cells Carcinoma : Correlation With Immunohistochemistry

Hypoxia imaging has not been studied extensively by combining PET and MRI data. Few studies performed the double imaging and none associated anatomopathology with it . This study will use a rigorous methodology through the production of PET/MRI images at the same time by transferring the patient directly from PET to MRI. In addition, the population, unlike other studies, will include preoperative patients with 24-hour surgery for hypoxia imaging by obtaining additional data through specific immunohistochemical analysis of hypoxia.

Inclusion Criteria:

• Patient with squamous cells carcinoma of oropharynx
• Age Superior to 10 years old
• Male or Female
• measurable target according RECIST criteria

Exclusion Criteria:

• -Other histologic cancer than squamous cells carcinoma of oropharynx
• No measurable target
• Presence of metastasis