Ultrafiltration on Coagulation Function in Cardiac Surgery

Effect of Ultrafiltration Before Weaning From Cardiopulmonary Bypass on Post-bypass Coagulation Function in Cardiac Surgery

To determine the effect of modified ultrafiltration, which is usually employed for reducing free water at the end of cardiopulmonary bypass (CPB), on coagulation profile in patients undergoing cardiac surgery

Inclusion Criteria:

• patients undergoing elective cardiac surgery with cardiopulmonary bypass (CPB)
• maximal clot formation (MCF) in ROTEM-EXTEM is reduced (< 50.5 mm before applying ultrafiltration)

Exclusion Criteria:

• transfusion of packed RBC> 3 units during CPB
• total ultrafiltration volume < 250 ml
• hyperfibrinolysis (lysis% > 10%) before applying ultrafiltration