Super-Bolus: Effects on Postprandial Glycemia After High Glycemic Index Meal

Effects of Super-Bolus on Postprandial Glycemia After High Glycemic Index Meal in Children With Type 1 Diabetes Mellitus- Randomized Study

The aim of this study is to determine whether Super-Bolus is more effective in postprandial glycemic control than Normal-Bolus after the high glycemic index (H-GI) meal in children with type 1 diabetes (T1DM) treated with insulin pump (continuous subcutaneous insulin infusion, CSII).

Inclusion Criteria:

• duration of type 1 diabetes longer than 12months,
• insulin pump therapy longer than 3 months,
• written informed consent to participate in the study signed by parents (and patient older than 16 years).

Exclusion Criteria:

• celiac disease,
• diabetes related complications (e.g. nephropathy),
• BMI at or above the 95th percentile and at or below 3rd percentiles for children and teenagers of the same age and sex,
• withdrawal of consent to participate in the study,
• comorbid conditions and treatment which could significantly affect glycemic values in the researchers' opinion.