The Effects of Music Therapy on Near-infrared Spectroscopy and Electroencephalogram in Premature Infants

The Effects of Music Therapy on Near-infrared Spectroscopy and Electroencephalogram in Premature Infants

Music has been consistently shown magic power in brain plasticity. Several study proved music can influence electronic activity of preterm infants' brain, while none study covered region oxygen metabolic. The investigators aim to discover the effects of music therapy on near-infrared spectroscopy and electroencephalogram in premature infants.

Previous studies of music therapy have made some achievements for adult Parkinson's disease, schizophrenia, depression, anxiety, post-traumatic stress and pediatric autism spectrum disorders. For newborns, studies mainly focused on the effects of basic vital signs, feeding and pain score decreasing. So far, no studies evaluating the effect of music therapy on brain oxygen metabolic and electronic activity.

Inclusion Criteria:

• Postmenstrual age of 32-36+6 weeks.
• Appropriate weight for gestational age.
• To have signed an informed consent to participate in the study.
• Have reached clinical stability.

Exclusion Criteria:

• Have nervous system diseases or obvious nervous system symptoms.
• Severe congenital diseases.
• The maintenance of sedative or analgesic drugs.
• Support with mechanical ventilation.