Effects of a Circuit Training on Balance in Persons With Multiple Sclerosis

Effects of a Circuit Training on Balance Management in a State of Fatigue in Persons With Multiple Sclerosis

The aim of the study is to evaluate the effects of a circuit training rehabilitation program on the perceived impact of fatigue in daily life situations and on gait and balance. Half of the participants will follow the circuit training program, while the other half will follow usual care rehabilitation programs.

Approximately 80% of Persons with Multiple Sclerosis rates fatigue among the three most disabling symptoms. Aerobic, balance and strength training have already been proved effective in rehabilitation, especially for Persons with Multiple Sclerosis. Fifty-two Persons with Multiple Sclerosis will be randomly allocated to an experimental group or to a control group following usual care rehabilitation programs. Experimental group will follow a circuit training rehabilitation program which combines high intensity aerobic training with balance and strength training. The study aims to verify the effects of the circuit training program on fatigue and on balance in different contexts with respect to usual care rehabilitation programs and to investigate effects of rehabilitation on immunological markers.

Inclusion Criteria:

• Definite diagnosis of Multiple Sclerosis (Polman criteria);
• No relapses in the previous three months;
• Expanded Disability Status Scale < 6,5;
• Able to walk 20 meter with or without an assistive device;
• Able to stand for 30 second without aid;
• MiniMental State Examination >20;

Exclusion Criteria:

• Unable to understand the aim of the study or unable to sign the informed consent form;
• Subjects following a steroidal drug therapy or assuming drugs affecting cardiac function;
• Subjects with psychiatric disorders;
• Subjects with cardiovascular diseases for whom aerobic training is forbidden;