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Twenty patients referring to periodontics department of Boroujerd Azad university of dentistry after obtaining consent to participate in the research project, which have more than 20 teeth, are over 18 years old and require socket preservation surgery to tooth extraction for the periodontal problem, caries or Fractures were selected.
twenty healthy patients referring to periodontics department of Boroujerd Azad university of dentistry after obtaining consent to participate in the research project, which has more than 20 teeth, are over 18 years old and require socket preservation surgery to tooth extraction for the periodontal problem, caries or Fractures were selected. moreover, divided the socket randomly to two groups(A, B)including A: bone graft with lovastatin and B: bone graft alone, after 3 months with trephine will collect the samples. following the histomorphometric analysis.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| lovastatin 40 mg with bone graft | Active Comparator | after tooth extraction, put teh lovastatin40 mg wif bone graft wifin tooth socket |
|
| without drug with bone graft | Active Comparator | after tooth extraction, put the bone graft wifin tooth socket |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Lovastatin 40 MG | Drug | after tooth extraction, put teh lovastatin40 mg wif bone graft wifin tooth socket |
|
| Measure | Description | Time Frame |
|---|---|---|
| Socket preservation with Lovastatin as evaluated by the amount of bone formation volume | 3 month |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Amirhossein Farahmand, Assistant Prof | Contact | +98 912 404 0359 | perio-implant@hotmail.com |
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Amirhossein Farahmand | Recruiting | Tehran | 19 | Iran |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 42254059 | Derived | Farahmand A, Houshmand B, Shirazi AR, Attar Zadeh Y, Taghavi Namin S, Zohary M, Sadeghi MR. Socket preservation with and without lovastatin in combination with synthetic bone graft substitute: A double-blind clinical trial. J Adv Periodontol Implant Dent. 2026 Feb 2;18(2):80-89. doi: 10.34172/japid.026.3919. eCollection 2026 Apr. |
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| without drug with Bone graft | Procedure | after tooth extraction, put teh bone graft wifin tooth socket |
|
|
| ID | Term |
|---|---|
| D001851 | Bone Diseases, Metabolic |
| ID | Term |
|---|---|
| D001847 | Bone Diseases |
| D009140 | Musculoskeletal Diseases |
| D008659 | Metabolic Diseases |
| D009750 | Nutritional and Metabolic Diseases |
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| ID | Term |
|---|---|
| D008148 | Lovastatin |
| D004364 | Pharmaceutical Preparations |
| D016025 | Bone Transplantation |
| ID | Term |
|---|---|
| D009281 | Naphthalenes |
| D011084 | Polycyclic Aromatic Hydrocarbons |
| D006841 | Hydrocarbons, Aromatic |
| D006844 | Hydrocarbons, Cyclic |
| D006838 | Hydrocarbons |
| D009930 | Organic Chemicals |
| D011083 | Polycyclic Compounds |
| D016378 | Tissue Transplantation |
| D064987 | Cell- and Tissue-Based Therapy |
| D001691 | Biological Therapy |
| D013812 | Therapeutics |
| D019637 | Orthopedic Procedures |
| D013514 | Surgical Procedures, Operative |
| D014180 | Transplantation |
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