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To study the efficacy of magnesium sulphate as adjuvant to levobupivacaine in transversus abdominis plane (TAP) block in patient undergoing abdominal cancer surgery.
In this randomized study, patients with (ASA) Ó€ and Ó€Ó€, aged from 1 to 7 years old and their weight less than 30 Kg of both sex will undergo surgery will be enrolled.
A written informed consent from all parents are obtained
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| magnesium sulphate& levobupivacaine | Active Comparator | Levobupivacaine add to magnisum sulphate |
|
| levobupivacaine | Placebo Comparator | levobupivacaine |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| ultra-sound guided transversus abdominis plan block | Procedure | comparing ultrasound guided transversus abdominis plan block using combination of magnisum sulphate and levobupivacaine versus levobupivacaine |
| Measure | Description | Time Frame |
|---|---|---|
| postoperative pain management | pain will be assessed using FLACC score.The Face, Legs, Activity, Cry, Consolability (FLACC) pain score with its 0 - 10 score range will be used to assess pain immediately postoperative and then at 2, 4, 6, 8, 12, 18 and 24 hours in the postoperative period. | one day |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Ahmed K Sayed, specialist | Contact | 01010677881 | ahmedkamal86anathesia@gmail.com |
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| south Egypt cancer institute | Recruiting | Asyut | Egypt |
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Group A (control group): patients will receive levobupivacaine 0.25% . Group B (magnesium sulphate group): patients will receive levobupivacaine 0.25% + MgSo4 .
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all participant will be blinded to the study drugs.
| magnesium sulphate& levobupivacaine | Drug | magnesium sulphate& levobupivacaine |
|
| Levobupivacaine | Drug | levobupivacaine |
|
| ID | Term |
|---|---|
| D010149 | Pain, Postoperative |
| ID | Term |
|---|---|
| D011183 | Postoperative Complications |
| D010335 | Pathologic Processes |
| D013568 | Pathological Conditions, Signs and Symptoms |
| D010146 | Pain |
| D009461 | Neurologic Manifestations |
| D012816 | Signs and Symptoms |
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| ID | Term |
|---|---|
| D000077554 | Levobupivacaine |
| ID | Term |
|---|---|
| D002045 | Bupivacaine |
| D000813 | Anilides |
| D000577 | Amides |
| D009930 | Organic Chemicals |
| D000814 | Aniline Compounds |
| D000588 | Amines |
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