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| Name | Class |
|---|---|
| French Society of Anesthesia and Intensive Care Medecine | UNKNOWN |
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The primary purpose of the study is to evaluate treatment of new onset atrial fibrillation in french ICU.
Atrial fibrillation (AF) is a common arrhythmia in the ICU and is associated with significant morbidity. However, curative treatment remains unclearly established. In fact, there are no specific recommendations for new onset atrial fibrillation in ICU and only few studies have assessed this topic.
The PAF-ICU trial is an observational, prospective, multicenter, transversal trial. The main objective is to evaluate the management of paroxytic atrial fibrillation that occur in ICU.
The investigators want to document 2500 episodes of paroxystic atrial fibrillation in 50 ICU centers. In each center, the episodes are included consecutively until the required 50 episodes are obtained for each center.
A patient can present several episodes and each episode can be included in the study. A new episode is considered as such if it occurs more than one hour after the previous episode.
The follow-up period for each patient corresponds to the ICU stay.
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| Measure | Description | Time Frame |
|---|---|---|
| Management of Atrial Fibrillation | All types of therapeutics used to manage atrial fibrillation are collected | ICU stay (until 28 days) |
| Measure | Description | Time Frame |
|---|---|---|
| Cardiac rhythm status | Type of rhythm : Normal (sinus rhythm), Atrial Fibrillation, Other disturbance | Before, 5 minutes, 30 minutes, 1 hour, and 24 hours after atrial fibrillation |
| Blood pressure |
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Inclusion Criteria:
Exclusion Criteria:
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Patients hospitalized in French ICU
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| Name | Affiliation | Role |
|---|---|---|
| Jean-Michel Constantin | Réa Adulte CHU Clermont-Ferrand | Study Director |
| Bernard Cosserant | Neuro-Réa CHU Clermont-Ferrand | Principal Investigator |
| Raiko Blondonnet | RMC CHU Clermont-Ferrand | Principal Investigator |
| Eric Kipnis | CHU Lille | Principal Investigator |
| Jonathan Paillot | CHU Besancçon | Principal Investigator |
| Charles Vidal | CHU de la Réunion | Principal Investigator |
| Laurent Muller | CHU Nimes | Principal Investigator |
| Johann Auchabie | CH Cholet | Principal Investigator |
| Guillaume Grillet | CH Lorient | Principal Investigator |
| Philippe Seguin | Rennes University Hospital |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| CHU | Amiens | France | ||||
| CHU |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 41016469 | Derived | Pardo E, Futier E, Muller L, Besch G, Vardon-Bounes F, Kipnis E, Lasocki S, Ledochowski S, Ochin E, Bourenne J, Grillet G, Auvet A, Mekontso Dessap A, Bruel C, Launey Y, Fiorillo M, Jabaudon M, Godet T, Mulliez A, Constantin JM; SFAR Research Network. Management of new-onset atrial fibrillation in critically ill patients: A national multicenter prospective cohort. Anaesth Crit Care Pain Med. 2026 Jan;45(1):101617. doi: 10.1016/j.accpm.2025.101617. Epub 2025 Sep 26. |
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Blood pressure. Unit : Millimeters of mercury
| Before, 5 minutes, 30 minutes, 1 hour, and 24 hours after atrial fibrillation |
| Heart rate | Heart rate. Unit : beats per minute | Before, 5 minutes, 30 minutes, 1 hour, and 24 hours after atrial fibrillation |
| Cardiac output | Product of the heart rate (HR) and the stroke volume (SV), which is the volume of blood pumped from the ventricle per beat. Unit : L/min. | Before, 5 minutes, 30 minutes, 1 hour, and 24 hours after atrial fibrillation |
| ScvO2 | Venous saturation. Unit : percentage | Before, 5 minutes, 30 minutes, 1 hour, and 24 hours after atrial fibrillation |
| Vasopressors | Type of vasopressors used | Before, 5 minutes, 30 minutes, 1 hour, and 24 hours after atrial fibrillation |
| Stroke | Occurrence of stroke during ICU stay | ICU Stay up to 28 days |
| Principal Investigator |
| Philippe Guerci | CHRU Nancy | Principal Investigator |
| Bernard Lalanne | Hôpital Saint-Joseph - Marseille | Principal Investigator |
| Marc Leone | Hôpital Nord - APHM | Principal Investigator |
| Stanislas Ledochowski | CH Bourgoin-Jallieu | Principal Investigator |
| Matthieu Legrand | Hôpital Saint-Louis - APHP | Principal Investigator |
| Jeremy Bourenne | La Timone APHM | Principal Investigator |
| Michel Durand | University Hospital, Grenoble | Principal Investigator |
| Antoine Monsel | La Pitié Sapêtrière | Principal Investigator |
| Mathieu Guilbart | CHU Amiens | Principal Investigator |
| Matthieu Biais | University Hospital, Bordeaux | Principal Investigator |
| Cédric Bruel | CH Saint-Joseph Paris | Principal Investigator |
| Antoine Roquilly | Nantes University Hospital | Principal Investigator |
| Gaëtan Plantefeve | CH Argenteuil | Principal Investigator |
| Jérôme Morel | Centre Hospitalier Universitaire de Saint Etienne | Principal Investigator |
| Carole Ichai | Centre Hospitalier Universitaire de Nice | Principal Investigator |
| Adrien Auvet | CH Dax | Principal Investigator |
| Enora Atchade | Hôpital Bichat | Principal Investigator |
| Sigismond Lasocki | University Hospital, Angers | Principal Investigator |
| Pierre-Eric Danin | Clinique Les Sources Nice | Principal Investigator |
| Marc Danguy Des Deserts | Hôpital d'Instruction des Armées de Brest | Principal Investigator |
| Evelina Ochin Salatova | Hôpital Simone Veil - CH d'Eaubonne | Principal Investigator |
| Antoine Rouget | University Hospital, Toulouse | Principal Investigator |
| Armand Mekontso Dessap | Hôpital Henri Mondor APHP | Principal Investigator |
| Justine Perrot | CHU Dijon | Principal Investigator |
| Jibba Amraoui | Institut Régional du Cancer de Montpellier | Principal Investigator |
| Matthias Garot | CHU Lille | Principal Investigator |
| Angers |
| France |
| CH | Argenteuil | France |
| CHU | Besançon | France |
| CHU | Bordeau | France |
| CH | Bourgoin | France |
| Hôpital d'Instruction des Armées | Brest | France |
| CH | Cholet | France |
| CHU | Clermont-Ferrand | France |
| CH | Dax | France |
| CHU | Dijon | France |
| CH | Eaubonne | France |
| CHU | Grenoble | France |
| CHU | Lille | France |
| Hôpital du Scorff | Lorient | France |
| APHM | Marseille | France |
| Hôpital Saint-Joseph | Marseille | France |
| La Timone APHM | Marseille | France |
| Institut Régional du Cancer de Montpellier | Montpellier | France |
| CHU | Nancy | France |
| CHU | Nantes | France |
| CHU | Nice | France |
| Clinique médicale les Sources | Nice | France |
| CHU | Nîmes | France |
| Groupe Hospitalier Saint Joseph | Paris | France |
| Hôpital Bichat | Paris | France |
| Hôpital Henri Mondor | Paris | France |
| Hôpital La Pitié Salpêtrière | Paris | France |
| Hôpital Saint-Louis | Paris | France |
| CHU | Rennes | France |
| CHU | Saint-Etienne | France |
| CHU | Toulouse | France |