French and EuRopean Outcome Registry in Intensive Care Unit

French and EuRopean Outcome Registry in Intensive Care Unit

The purpose of this study is to identify within a cohort of ICU patients admitted for severe illness those who are at risk of death in the year following the discharge from ICU.

FROG-ICU is an epidemiological, observational, prospective, multi centric, cohort study designed for description, prognostic and evaluation. This trial includes as a first step a complete registry of patients admitted to the ICU and as a second step, the outcome of the patients at 1 year after they have been discharged alive from ICU.

Plasma and urine samples will be with drawn biomarkers measurements at admission and ICU discharge. It is a multicentric study involving 1 center in Belgium et 24 centers in France.

Inclusion criteria:

• Adult patients hospitalized in ICU
• Patients should have been intubated more than 24 hours
• or treated with a positive inotropic agent for more than 24 hours (if not ventilated

Exclusion Criteria:

• age < 18 years
• pregnancy women
• Breast-feeding women
• Not affiliated with social security
• Dying man
• End of life patient
• Traumatic Brain Injury (IGCS < 8)
• NTBR
• vegetative coma
• Transplanted for less than year
• no french speaking patient
• out of france resident
• end of life decision during the following