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The aim of this study is to evaluate the remineralization potential of pearl powder on early ('white spot') lesions in enamel in orthodontic patients compared to casein phosphopeptide-amorphous calcium phosphate.
The aim of this study is to evaluate the remineralization potential of pearl powder on early ('white spot') lesions in enamel in orthodontic patients compared to casein phosphopeptide-amorphous calcium phosphate. The remineralisation potential will be assessed both visually and by standardised photographic image analysis. the follow up will be up to 12 months.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Cpp-acp | Active Comparator | MI paste Self-administration of the product by the patient once in the evening. A pea-size amount of the product should be applied per arch, using a dry finger or cotton pellet to distribute it evenly across all teeth and to work it into the interdental spaces. The product was then retained in the mouth for 1-3 min, and manipulated around the teeth using the tongue, before being expectorated and patient should not rinse it until 30 min. |
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| Pearl powder | Experimental | Pure pearl powder in the form of gel Self-administration of the product should be used once daily (in the evening), after a 2 min manual tooth brushing. .Participants were explicitly instructed to apply the gel by his finger allover the teeth and not to rinse their mouths after application and not to eat or drink for at least 30 min. |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Cpp-Acp | Drug | Remineralising agent |
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| Measure | Description | Time Frame |
|---|---|---|
| Clinical index used for visual evaluation of white spot lesions | Scores(0-No visible colour change, 1-Slight white colour change, only visible after air-drying, 2-Slight colour change with certain marked white areas, 3-White consistent colour change, 4-Distinct white colour change) | 12 months |
| Measure | Description | Time Frame |
|---|---|---|
| Digital photographic image analysis | Computerised software to analyse the change in the lesion | 12 months |
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Inclusion Criteria:
Exclusion Criteria:
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| ID | Term |
|---|---|
| C447032 | casein phosphopeptide-amorphous calcium phosphate nanocomplex |
| C000719515 | pearl powder |
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| Pearl powder |
| Other |
Natural product |
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