Intravenous Ascorbic Acid Administration in Hysterectomy

Effect of Ascorbic Acid Administration on Intraoperative Blood Loss and Wound Healing in Total Abdominal Hysterectomy

vitamin C or ascorbic acid has known role in tissue repair. due to it's properties(water_soluble), vitamin c is not stored in the body and when depleted, the bleeding tendency will increase due to dysfunctional connective tissues production in vessel wall and it has some important functions in platelets.

In this randomized clinical trial, 1000 mg vitamin C will administrate intravenously a day before surgery and during surgery in patients who undergo abdominal hysterectomy.

Inclusion Criteria:

• To be 18 years and older
• No smoking
• No history of bleeding disorder
• No history of favism
• No history of uterus, ovary, cervical cancer

Exclusion Criteria:

• Need to injection of vasopressor drugs
• Surgeon disagreement