Impact of Nicotine on Retinal Vascularization

Impact of Nicotine on Retinal Vascularization (Tabaret)

The main hypothesis is the nicotine is associated with a modification of retinal micro-vascularization.

Patients will be recruited during their ophthalmologic consultation at the Rothschild Foundation, an OCT-A will be realized and data relating to medical history, oral contraceptive intake and nicotine consumption via cigarette or e-cigarette data will be collected.

The objective is to seek an association between retinal vascular density and inhaled nicotine intake.

Inclusion criteria

• For group of smokers: Patient reporting active smoking for at least 3 months and at least 1 cigarette per day on average over a week
• For group of vapers : Patient using exclusively the electronic cigarette with a nicotine level of more than 6mg/ml for at least 3 months and at least 1 times per day on average over a week.
• For group of no-smokers no-vapersNon-smoking and no vaping, for more than 6 months

Non-inclusion criteria:

• Caffeine intake within 2 hours prior to the OCT-A exam
• ametropia greater than + 3 dioptres of hyperopia or-3 dioptres of myopia
• astigmatism greater than 2 dioptres
• Known retinal or retina vascular pathology