To evaluate the effect of wound infiltration with 0.25% Bupivacaine in laparoscopic cholecystectomy in terms of pain severity, patient satisfaction level, quality of life, hospital stay and return to job and normal activities.

Inclusion criteria

• Patients scheduled to undergo laparoscopic cholecystectomy under general anesthesia at department of surgery and department of hepatobiliary system, BSMMU
• Patients who are eligible according to ASA Ⅰ -Ⅱ
• Female or male, age ≥18 years
• Patients who are scheduled for same anesthetic technique and surgical procedure for laparoscopic cholecystectomy
• Discharge of patient between 12 hour to 36 hour after performing procedure
• Patients given consent for enrollment in study

Exclusion criteria

• Patients known to be allergic to certain recommended drugs
• If patients have history of psychiatric illness
• Patients on chronic analgesic therapy for any other indication
• Patients who are scheduled for different anesthetic technique and surgical procedure for laparoscopic cholecystectomy
• Duration of surgery more than 1 hour
• Patients undergoing laparoscopic cholecystectomy for complex gallbladder disease such as incidental gallbladder pancreatitis, gallstone pancreatitis, cholecystoduodenal fistula, mirizzi syndrome
• Special population group such as children, pregnant woman, patients with cirrhosis, diabetics
• Duration of operative procedure more than 1 hour