The purpose of this study is to evaluate the effectiveness of two behavioral interventions on smoking behavior - Mindfulness-Oriented Recovery Enhancement (MORE) and Cognitive Behavioral Therapy (CBT). MORE is a behavioral therapy that integrates mindfulness training to modify reward processes. CBT is a therapy designed to help individuals understand how their thoughts and feelings influence their behaviors.

Inclusion Criteria:

• Age 18 and up
• English fluency as demonstrated in providing informed consent and the ability to independently follow directions in completing assigned assessments and tasks
• Functional vision (with corrective lenses as needed) to complete assigned assessments and tasks
• Current nicotine dependent smoker with a minimum smoking history of 2 years
• Interest in quitting smoking

Exclusion Criteria:

• Use of psychotropic (e.g. antiepileptic) medications in the past month
• Positive urine drug screen
• Presence of an untreated medical illness
• Current or past psychosis
• History of major neurological illness or head injury resulting in loss of consciousness
• And contraindication to MRI, including claustrophobia
• Among females, positive urine pregnancy test
• Inability or unwillingness of subject to give informed consent