Diffusion Tensor Imaging of Median Nerve in Diabetic Peripheral Neuropathy

A Study of Diffusion Tensor Imaging of Median Nerve in Diabetic Peripheral Neuropathy

This study is a diagnostic accuracy study that aims to evaluate the role of DTI in evaluation of DPN in comparison to clinical scores and nerve conduction studies (NCS). The study included 30 patients with diabetes mellitus complaining of neuropathy symptoms and 15 healthy volunteers. All subjects underwent evaluation using 1.5T DTI of median nerves and NCS. Patients underwent clinical evaluation using Neuropathy Deficit Score (NDS), Neuropathy Impairment Score in the Lower Limbs (NIS-LL) and Diabetic Neuropathy Examination (DNE) score. The values of these tests were compared and correlated and diagnostic accuracy tests were performed together with identification of cut-off score for abnormal diffusion tensor imaging parameters in diabetic neuropathy

Inclusion Criteria:

• Diabetic patients with symptoms suggestive of peripheral neuropathy.

Exclusion Criteria:

• Patients with evidence of nerve entrapment or neuropathy due to causes other than DM