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| Name | Class |
|---|---|
| Maoming People's Hospital | OTHER |
| Dongguan People's Hospital | OTHER_GOV |
| Southern Medical University, China | OTHER |
| Guangzhou Panyu Central Hospital |
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Incidence of ST-segment Elevation Myocardial Infarction (STEMI) is rising and the existing emergency medical aid system for STEMI was not enough for timely perfusion treatment. No existing research with high-quality data focuses on the characteristic of STEMI incidence and regional network construction. Aiming of Guangdong GAMI(reGional network for Acute Myocardial Infarction) project is to establish effective collaborative regional network system for STEMI patients treatment.
The project of Guangdong GAMI(reGional network for Acute Myocardial Infarction) is being conducted during 2015-2019 in eight districts with diverse economic development across southern China (Integrated care model was conducted in four regions, which mainly included community public education, non primary-PCI capable centre and referral system improvement, and inhospital green-channal optimization for primary-PCI capable centre. Other four centers were underwent usual care of acute myocardial infacrtion public and medical health service). All the ST-segment elevation myocardial infarction (STEMI) patients admitted in the hospital within 30 days from the symptom onset were enrolled. The key data of the timeline of STEMI onset and treatment were precisely recorded. Other details of STEMI treatment in hospitals such as laboratory data and medication were also collected. During the research period, actions of both optimizing the regional STEMI patients transfer and treatment to shorten the medical delay, as well as educating the public to improve their awareness of early treatment of STEMI were taken meanwhile. In addition, laboratory data, medication, and follow-up information were recorded in a database for further analysis regarding the STEMI patient treatment.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Intervention group | Experimental | community public education, non-PCI center and emergency transfer system improvement, and inhospital green-channal optimization for PCI center. |
|
| Control group | No Intervention | Usual care of AMI public and medical health service |
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| public education and network construction | Behavioral | Publication education includes multiple methods of acute myocardial infarction knowledge education. Network construction includes regional connection of ST-Segment Elevation Myocardial Infarction patients transfer for percutaneous coronary intervention treatment, as well as physicians skill improvement in primary hospital. |
| Measure | Description | Time Frame |
|---|---|---|
| Receipt of reperfusion therapy within 12 hoursInfarction patients | The primary outcome was the proportion of patients who received symptom-to-reperfusion treatment within 12 hours. | From 1 month before hospitalization to 24 hours after hospitalization |
| Measure | Description | Time Frame |
|---|---|---|
| Onset-to-admission time within 12 hours | The proportion of patients who take a symptom-to-admission period within 12 hours. | From 1 month before hospitalization to 24 hours after hospitalization |
| Door-to-balloon time within 90 minutes |
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Inclusion Criteria:
All adult patients who suspected diagnosis with STEMI.
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Yan Liang, MD | Maoming People's Hospital | Principal Investigator |
| Jianfeng Ye, MD | Dongguan People's Hospital | Principal Investigator |
| Yunzhao Hu, MD | The first People's Hospital of Shunde, Foshan | Principal Investigator |
| Wenzhu Zhang, MD | Guangzhou Panyu Central Hospital | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Longyan First Hospital Affiliated to Fujian Medical University | Longyan | Fujian | 364000 | China | ||
| Dongguan People's Hospital |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 26729395 | Background | Lu J, Xuan S, Downing NS, Wu C, Li L, Krumholz HM, Jiang L. Protocol for the China PEACE (Patient-centered Evaluative Assessment of Cardiac Events) Million Persons Project pilot. BMJ Open. 2016 Jan 4;6(1):e010200. doi: 10.1136/bmjopen-2015-010200. | |
| 32580976 | Background | Yin X, He Y, Zhang J, Song F, Liu J, Sun G, Liang Y, Ye J, Hu Y, Song M, Chen C, Xu Q, Tan N, Chen J, Liu Y, Liu H, Tian M. Patient-level and system-level barriers associated with treatment delays for ST elevation myocardial infarction in China. Heart. 2020 Oct;106(19):1477-1482. doi: 10.1136/heartjnl-2020-316621. Epub 2020 Jun 24. |
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| ID | Term |
|---|---|
| D003327 | Coronary Disease |
| D000072657 | ST Elevation Myocardial Infarction |
| ID | Term |
|---|---|
| D017202 | Myocardial Ischemia |
| D006331 | Heart Diseases |
| D002318 | Cardiovascular Diseases |
| D014652 | Vascular Diseases |
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| OTHER |
| Yangjiang People's Hospital | OTHER |
| Shenzhen People's Hospital | OTHER |
| Longyan First Hospital, Affiliated to Fujian Medical University | UNKNOWN |
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|
The proportion of patients who take a door-to-balloon period within 90 minutes.
| 24 hours |
| In-hospital clinical outcomes | The incidence of several in-hospital outcomes (in-hospital death; and major adverse cardiac events [MACEs], which mainly included in-hospital death, recurrence of myocardial infarction, and stroke); the length of stay. | 30 days |
| 1-year all-cause mortality | Total mortality between 30 days and 1 year after discharge. | 1 year |
| Dongguan |
| Guangdong |
| 523000 |
| China |
| Shunde Hospital of Southern Medical University | Foshan | Guangdong | 528000 | China |
| Guangdong Provincial People's Hospital | Guangzhou | Guangdong | 501080 | China |
| Guangzhou Panyu Central Hospital | Guangzhou | Guangdong | 511400 | China |
| Maoming People's Hospital | Maoming | Guangdong | 525000 | China |
| Shenzhen People's Hospital | Shenzhen | Guangdong | 518000 | China |
| People's Hospital of Yangjiang | Yangjiang | Guangdong | 529500 | China |
| 40930595 | Derived | Liu Y, Liu J, Liang Y, Ye J, Hu Y, Chen L, Dong S, Huang X, Song M, Meng R, Zheng X, He Y, Zhang J, Yin X, Chen S, Tan N, Tian M, Chen J. Effect of an integrated care model on ST-segment elevation myocardial infarction management in China: a prospective, multicentre, non-randomised controlled study. Heart. 2025 Sep 9:heartjnl-2024-324155. doi: 10.1136/heartjnl-2024-324155. Online ahead of print. |
| D009203 |
| Myocardial Infarction |
| D007238 | Infarction |
| D007511 | Ischemia |
| D010335 | Pathologic Processes |
| D013568 | Pathological Conditions, Signs and Symptoms |
| D009336 | Necrosis |