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| Name | Class |
|---|---|
| Shandong Provincial Hospital | OTHER_GOV |
| Qianfoshan Hospital | OTHER |
| Jinan Central Hospital | OTHER |
| The Second Hospital of Shandong University |
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EAST-STEMI is the first perspective, multicenter, large-scale registry focusing on the evaluation of real-world medical quality (especially PCI quality) and antithrombotic strategies in STEMI patients undergoing emergent PCI in a regional representative sample in China with 2 years follow-up. Clinical decision support tools (including ischemic score, bleeding score, etc) will be developed and validated based on the database. Novel biomarkers to predict the prognosis and to support risk stratification will be explored by using the blood samples.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| STEMI patients undergoing Emergent PCI |
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| Measure | Description | Time Frame |
|---|---|---|
| Net Adverse Clinical Events (NACEs) | The primary outcome is the rate of adjudicated NACEs, a composite of major adverse cardiac or cerebral events (MACCEs) and bleeding. MACCEs include cardiac death, reinfarction, urgent revascularization, or stroke. Bleeding is defined by the Bleeding Academic Research Consortium (BARC) definition (types 1-5). BARC type 2 bleeding is considered as minor bleeding, type 3-5 bleeding is considered as major bleeding. | 2 years after emergent PCI |
| Measure | Description | Time Frame |
|---|---|---|
| Contrast-induced acute kidney injury (CI-AKI) | CI-AKI is defined as an increase in serum creatinine of ≥0.3mg/dl or ≥50% from baseline within 72 hours. | 72 hours after contrast exposure |
| Definite/Probable Stent thrombosis |
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Inclusion Criteria:
Exclusion Criteria:
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consecutive STEMI patients undergoing emergent PCI
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| Name | Affiliation | Role |
|---|---|---|
| Yuguo Chen, Dr | Qilu Hospital of Shandong University | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Qilu Hospital of Shandong University | Jinan | Shandong | 250012 | China |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 41985625 | Derived | Wu S, Wang S, Xu F, Pang J, Chen Y. High Kidney Function in Myocardial Infarction Patients Who Underwent Coronary Intervention: Acute Kidney Injury Risk and Long-term Prognosis. Can J Cardiol. 2026 Apr 13:S0828-282X(26)00354-5. doi: 10.1016/j.cjca.2026.04.001. Online ahead of print. |
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| ID | Term |
|---|---|
| D000072657 | ST Elevation Myocardial Infarction |
| ID | Term |
|---|---|
| D009203 | Myocardial Infarction |
| D017202 | Myocardial Ischemia |
| D006331 | Heart Diseases |
| D002318 | Cardiovascular Diseases |
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| OTHER |
| Shandong Province Third hospital | OTHER |
| The 5th People's Hospital of Jinan | UNKNOWN |
| The 6th People's Hospital of Jinan | UNKNOWN |
| The Affiliated Hospital of Qingdao University | OTHER |
| Qingdao Municipal Hospital | OTHER |
| Qingdao Central Hospital | OTHER |
| Qingdao Haici Hospital | OTHER |
| Chengyang People's Hospital | UNKNOWN |
| Qingdao Westcoast New Area Central Hospital | UNKNOWN |
| Qingdao Jiaozhou Central Hospital | UNKNOWN |
| Pingdu People's Hospital | UNKNOWN |
| Central Hospital of Zibo | OTHER |
| Zibo First Hospital | OTHER |
| Linzi District People's Hospital | UNKNOWN |
| Peking University Care Luzhong Hospital | OTHER |
| Tengzhou Central People's Hospital | OTHER_GOV |
| Dongying People's Hospital | OTHER |
| Shengli Oilfield Hospital | OTHER |
| Yantaishan Hospital | UNKNOWN |
| Yantai Yuhuangding Hospital | OTHER |
| Yantai Affiliated Hospital of Binzhou Medical University | OTHER |
| Longkou People's Hospital | UNKNOWN |
| Laizhou City People's Hospital | OTHER |
| Weifang People's Hospital | OTHER |
| Weifang Medical University | OTHER |
| Weifang Traditional Chinese Medicine Hospital | OTHER |
| Yidu Central Hospital of Weifang | UNKNOWN |
| Qingzhou People's Hospital | UNKNOWN |
| Shouguang people's Hospital | UNKNOWN |
| Jining Medical University | OTHER |
| Jining First People's Hospital | OTHER |
| Wenshang People's Hospital | UNKNOWN |
| Affiliated Hospital of Jining Medical University | OTHER |
| Jinxiang People's Hospital | UNKNOWN |
| Taian City Central Hospital | OTHER |
| Taishan Medical University Affiliated Hospital | OTHER |
| Feicheng People's Hospital | UNKNOWN |
| Weihai Municipal Hospital | OTHER |
| Weihai Central Hospital | OTHER |
| Binzhou Medical University | OTHER |
| Zhouping People's Hospital | UNKNOWN |
| Dezhou People's Hospital | OTHER |
| Ningjin County People's Hospital | UNKNOWN |
| Liaocheng People's Hospital | OTHER |
| The Second People's Hospital of Liaocheng | UNKNOWN |
| Linyi People's Hospital | OTHER |
| Feixian People's Hospital | UNKNOWN |
| Heze Municipal Hospital | OTHER |
| Yuncheng County People's Hospital | UNKNOWN |
| Heze Luxin Cardiovascular and Cerebrovascular Hospital | UNKNOWN |
| Jining Integrative Medicine Hospital | UNKNOWN |
| Tianjin Chest Hospital | OTHER |
| Henan Provincial People's Hospital | OTHER |
| Inner Mongolia People's Hospital | OTHER |
| Anhui Provincial Hospital | OTHER_GOV |
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Stent thrombosis is defined according to the Academic Research Consortium criteria. Definite stent thrombosis is defined as angiography or autopsy examination confirmed stent occlusion or thrombus. Probable stent thrombosis is defined as death occurring within 30 days that cannot be attributed to another cause or when myocardial infarction occurs at any time point and is attributable to the target vessel in the absence of angiography confirming another culprit lesion.
| 2 years after emergent PCI |
| Heart failure | Heart failure is defined as physician documentation or report of any of the following clinical symptoms of heart failure described as unusual dyspnea on light exertion, recurrent dyspnea occurring in the supine position, fluid retention; or the description of rales, jugular venous distension, pulmonary edema on physical exam, or pulmonary edema on chest x-ray. A low ejection fraction alone, without clinical evidence of heart failure does not qualify as heart failure. | 2 years after emergent PCI |
| Quality of life (QoL) | QoL is assessed by using EuroQol-5 Dimension (EQ-5D), which is the most widely used generic instrument to measure QoL. The utility index scores of EQ-5D represent the QoL.The higher the score, the better the QoL. | 2 years after emergent PCI |
| D014652 |
| Vascular Diseases |
| D007238 | Infarction |
| D007511 | Ischemia |
| D010335 | Pathologic Processes |
| D013568 | Pathological Conditions, Signs and Symptoms |
| D009336 | Necrosis |