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Protective ventilation decreased morbidity and mortality in adults' patients and is now a standard of care in intensive care unit and in anesthesiology. In children, there is no evidence in the literature to recommend protective ventilation during anaesthesia. Moreover the ratio of instrumental dead space to tidal volume is higher in children than in adults. Therefore, it is difficult to propose an "optimal" tidal volume for all children. The objective of this study is to evaluate the use of alveolar ventilation (estimated by the volumetric capnography) in children under anesthesia. The hypothesis is that in children, alveolar ventilation reported to ideal body weight is a constant to maintain normocarbia, unlike the tidal volume.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Children between 5-10Kg | Children with a body weight between 5-10Kg |
| |
| Children between 10-20Kg | Children with a body weight between 10-20Kg |
| |
| Children between 20-40Kg | Children with a body weight between 20-40Kg |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Alveolar ventilation monitoring estimated by the capnographic ventilation | Other | Children are monitored using end-tidal CO2, Transcutaneous CO2 and volumetric capnographic. Respiratory rate is set using textbooks and guidelines (pediatric advanced life support). The physician in charge adapts the volume to target a CO2 between 38 and 42 mmHg. Data are recorded after a stabilization period of at least 5 minutes. |
| Measure | Description | Time Frame |
|---|---|---|
| Determination of target alveolar minute volume to maintain normocapnia in children without mechanical ventilation. | The minute alveolar ventilation estimated by the volumetric capnography reported to the ideal body weight based on 100 breaths (expressed in ml/Kg/min). | 5 minutes after hemodynamic and ventilatory stabilization period |
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Inclusion Criteria:
Exclusion Criteria:
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Children under general anaesthesia
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Pediatric anesthesia division, Hôpital Femme Mère Enfant, Hospices Civils de Lyon | Bron | 69500 | France |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 37052073 | Result | Gardon A, De Queiroz Siqueira M, Cerceuil E, Bouhamri N, Chassard D, Baudin F. Alveolar target ventilation and dead space in children under anaesthesia: The proventiped cohort study. Eur J Anaesthesiol. 2023 Jul 1;40(7):495-500. doi: 10.1097/EJA.0000000000001832. Epub 2023 Apr 12. |
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| ID | Term |
|---|---|
| D007431 | Intraoperative Complications |
| ID | Term |
|---|---|
| D010335 | Pathologic Processes |
| D013568 | Pathological Conditions, Signs and Symptoms |
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