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The aim of this study is to evaluate the effect of high-flow nasal cannula oxygen administration on apnea in patients undergoing general anesthesia with rigid bronchoscopy compared with standard anesthesia methods.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Optiflow | Experimental | 100 % of oxygen at 70 L / min through Optiflow â„¢ (Fisher and Paykel Healthcare Limited, Auckland, New Zealand) |
|
| Standard | No Intervention | standard anesthesia |
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Optiflow â„¢ | Device | supply of 100 % of oxygen at 70 L / min through Optiflow â„¢ (Fisher and Paykel Healthcare Limited, Auckland, New Zealand) plus standard oxygen supply through rigid bronchoscope during apnea period. |
| Measure | Description | Time Frame |
|---|---|---|
| the lowest oxygen saturation | the lowest value of oxygen saturation measured percutaneously at extremity. | apnea period during the rigidbroscopic procedure/surgery |
| Measure | Description | Time Frame |
|---|---|---|
| Hypoxia occurs the first time | intraoperative (The time taken to reach the point at which peripheral oxygen saturation fell below 90 for the first time immediately after the onset of apnea) | |
| End-tidal carbon dioxide partial pressure | Intraoperative (end-tidal CO2 partial pressure after 3 consecutive breaths after intubation or insertion of laryngeal mask following end of apnea) |
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Inclusion Criteria:
Exclusion Criteria:
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Department of Anesthesiology and Pain Medicine , Anesthesia and Pain Research Institute, Yonsei University College of Medicine | Seoul | 120-752 | South Korea |
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| ID | Term |
|---|---|
| D005547 | Foreign Bodies |
| D009369 | Neoplasms |
| D014135 | Tracheal Stenosis |
| D001984 | Bronchial Neoplasms |
| ID | Term |
|---|---|
| D014947 | Wounds and Injuries |
| D014133 | Tracheal Diseases |
| D012140 | Respiratory Tract Diseases |
| D008175 | Lung Neoplasms |
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A prospective Randomized, open label Trial
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triple (Participant, Care Provider, investigator)
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| Arterial oxygen / carbon dioxide partial pressure | shortly before start of apnea (within 30 seconds) |
| Arterial oxygen / carbon dioxide partial pressure | shortly after end of apnea (within 30 seconds) |
| hypoxemia related surgical interruptions | 4) hypoxemia related surgical interruptions during apneic period |
| D012142 |
| Respiratory Tract Neoplasms |
| D013899 | Thoracic Neoplasms |
| D009371 | Neoplasms by Site |
| D001982 | Bronchial Diseases |