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By clinical record review, this retrospective study aims to compare the different age groups of patients with obstructive sleep apnea, who were diagnosed and treated in Taipei Veterans General Hospital, Taiwan.
This retrospective study aims to compare the characteristics of patients with obstructive sleep apnea (OSA). Patients with sleep problem and received a prior polysomnography at Taipei Veterans General Hospital during Jan. 1, 2016 to Dec. 31, 2017 will be enrolled. Obstructive sleep apnea (OSA) is defined by an apnea-hypopnea index(AHI) at least 5/hr with compatible symptoms. Their clinical record will be reviewed and data including demography, polysomnography, comorbidities and details related to upper airway structure will be collected. The charactereistics would be compared with Student's t tests, Mann-Whitney U tests, or Chi square tests if appropriated.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Young adult, without OSAS | 20<=Age<40 years old, apnea-hypopnea index(AHI)<5 |
| |
| Young adult, with OSAS | 20<=Age<40 years old, AHI>=5 |
| |
| older adult, without OSAS | Age>=40 years old, AHI<5 | ||
| older adult, with OSAS | Age>=40 years old, AHI>=5 |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Age | Other | Age<40 years old is chosen as the cutoff value. |
|
| Measure | Description | Time Frame |
|---|---|---|
| Apnea-hypopnea index(AHI) | Counts of apnea/hypopnea events per hour | through study completion, an average of 1 year |
| Measure | Description | Time Frame |
|---|---|---|
| Body mass index(BMI) | The body mass divided by the square of the body height. | through study completion, an average of 1 year |
| Posterior airway space (PAS) | The diameter from supramentale to gonion. |
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Inclusion Criteria:
Exclusion Criteria:
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Adults with sleep complaints
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Chest department, Taipei Veteran General Hospital | Recruiting | Taipei | 112 | Taiwan |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 36447027 | Derived | Chiu HY, Chou KT, Su KC, Lin FC, Liu YY, Shiao TH, Chen YM. Obstructive sleep apnea in young Asian adults with sleep-related complaints. Sci Rep. 2022 Nov 29;12(1):20582. doi: 10.1038/s41598-022-25183-5. |
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| ID | Term |
|---|---|
| D000375 | Aging |
| ID | Term |
|---|---|
| D048788 | Growth and Development |
| D010829 | Physiological Phenomena |
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| OSA | Other | The diagnosis of OSA (obstructive sleep apnea) relies on polysomnographic data showing an apnea-hypopnea index at least 5/hr with compatible symptoms. |
|
| through study completion, an average of 1 year |
| Number of participants with comorbidities | Self-reported comorbidities including cardiovascular disease, stroke, hypertension, diabetes mellitus, hyperlipidemia, lung disease, anxiety, depression. | through study completion, an average of 1 year |
| Sleep efficiency | The ratio of the total time spent asleep (total sleep time) in a night compared to the total amount of time spent in bed. | through study completion, an average of 1 year |
| arousal index | The number of arousals and awakenings as a frequency per hour of sleep. | through study completion, an average of 1 year |
| oxygen desaturation index | The number of times per hour of sleep that the blood's oxygen level drop by 4% from baseline. | through study completion, an average of 1 year |