Accelerated Aging in Middle-Aged Men With Sleep-disordered Breathing.

Accelerated Aging in Middle-Aged Men With Sleep-disordered Breathing.

Obstructive Sleep Apnea Syndrome (OSAS) regardless of any other associated risk factor can lead to accelerated aging. The study of aging-related Obstructive Sleep Apnea (OSA) is difficult because of associated risk factors (diabetes, hypertension, dyslipidemia, obesity), promoting themselves aging. The investigators propose to compare a group of OSAS patients free of any associated pathology, to subjects matched for age, sex, smoking and body mass index (BMI)

Inclusion Criteria

Patient:

• Men aged 20 to 65 years
• Having polysomnography in the Functional Explorations department, Sleep Laboratory, Hospital Henri Mondor, Creteil
• With an AHI > 5 / h

Healthy volunteers:

• Men aged 20 to 65 years
• With an AHI ≤ 5 / h

Exclusion Criteria

All subjects:

• Known cardiovascular risk: hypertension treated, diabetes treated, dyslipidemia treated,
• Known cardiovascular disease associated (heart failure, rhythm disorder ...)
• Known respiratory diseases
• Known neoplastic pathology, known chronic inflammatory disease
• Psychiatric pathology treated
• Medication
• Not affiliated to the French social health care system
• Major protected person
• Private person of liberty
• People in emergency situation
• Patient refusing to participate in the study