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This study will be conducted to evaluate the effectiveness of using dissolving Xylitol chewable tablets versus xylitol chewing gum with bedridden geriatric patients in increasing salivary pH and decreasing bacterial count in both saliva and interdental plaque.
This study will be conducted to evaluate the value of using dissolving Xylitol chewable tablets versus xylitol chewing gum with bedridden geriatric patients ,as an alternative to tooth brushing and mouth rinsing, in increasing salivary pH and decreasing bacterial count in both saliva and interdental plaque.plaque and salivary sampling will be taken in certain time ,at baseline T0, then after 5minutes T1, then at 15 days T3. Salivary pH will be measured by using pH meter and streptococcus mutans bacterial count will be calculated through culture in mitis salivarius bacitracin
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Dissolving xylitol chewable tablets | Experimental | Listerine ready tabs 3 times/day |
|
| Xylitol chewing gum | Active Comparator | Trident original 3 times/day |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Listerine ready tabs | Drug | Technically, it's a rectangular-shaped, bilayer-compressed tablet that once chewed, creates just enough liquid to swish around your mouth to get a whole-mouth clean feeling.As manufacture claimed the tablet is easy to use just in three simple steps: chew (to activate), swish (to clean), then swallow as unlike mouthwashes which may contain alcohol and other ingredients not intended for ingestion, Listerine Ready Tabs are alcohol-free and safe to swallow which is highly suitable for bedridden patients. |
| Measure | Description | Time Frame |
|---|---|---|
| Salivary bacterial count | Streptococcus mutans count in saliva | 15 days |
| Measure | Description | Time Frame |
|---|---|---|
| Interdental plaque Bacterial count | Mesial and distal Interdental plaquns streptococcus mutans count | 15 days |
| Measure | Description | Time Frame |
|---|---|---|
| Salivary pH | Degree of acidity or alkalinity of salivary pH | 15 days |
Inclusion Criteria:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Manar MA Abd elmageed, Resident | Contact | +021287766120 | dentalmena90@gmail.com | |
| Department Of Conservative dentistry, Department | Contact | +0201068685923 | operative@dentistry.cu.edu.eg |
| Name | Affiliation | Role |
|---|---|---|
| Faculty Of Dentistry, Faculty | Cairo University | Study Director |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Faculty of dentistry | Al Manyal | Giza Governorate | +02 | Egypt |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 30123770 | Background | Oza S, Patel K, Bhosale S, Mitra R, Gupta R, Choudhary D. To Determine the Effect of Chewing Gum Containing Xylitol and Sorbitol on Mutans Streptococci and Lactobacilli Count in Saliva, Plaque, and Gingival Health and to Compare the Efficacy of Chewing Gums. J Int Soc Prev Community Dent. 2018 Jul-Aug;8(4):354-360. doi: 10.4103/jispcd.JISPCD_54_18. Epub 2018 Jul 18. |
| Label | URL |
|---|---|
| Free PMC article | View source |
| ID | Type | URL | Comment |
|---|---|---|---|
| Pubmed | Individual Participant Data Set | View IPD |
A paper of the research will be published internationally after results calculation
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| Type | Includes Protocol | Includes SAP | Includes ICF | Document Label | Document Date | Document Uploaded Date | Document File Name |
|---|---|---|---|---|---|---|---|
| Prot | Yes | No | No | Study Protocol | Mar 1, 2019 | Mar 13, 2019 | Prot_000.pdf |
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| ID | Term |
|---|---|
| D058225 | Plaque, Amyloid |
| D003773 | Dental Plaque |
| ID | Term |
|---|---|
| D020763 | Pathological Conditions, Anatomical |
| D013568 | Pathological Conditions, Signs and Symptoms |
| D003741 | Dental Deposits |
| D014076 | Tooth Diseases |
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Geriatric bedridden patients
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The operator will be blinded to material and assessors will be blinded to the material assignment.
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| D009057 | Stomatognathic Diseases |