Fractional Laser Assisted Delivery of Sculptra® for the Treatment of Striae

Fractional Laser Assisted Delivery of Sculptra® for the Treatment of Striae: FADeS Trial

This study evaluates the efficacy of treatment of striae distensae using the combined modality of fractional laser and poly-L lactic acid (Sculptra).

Striae Distensae (SD) is a form of scarring that can oftentimes be quite disfiguring and emotionally distressing to individuals.

Fractional laser therapy has been used by doctors to treat stretch marks by stimulating collagen growth.

Poly-L lactic acid also promotes collagen growth in the areas injected.

The combination of laser and poly-L lactic acid might provide the optimal treatment modality for SD by decreasing the appearance of atrophic scars.

Inclusion Criteria:

• Subject has bilateral striae alba
• Subject has stable body weight for at least 6 months with Fitzpatrick skin type 1-4

Exclusion Criteria:

• Subject has striae rubra
• Pregnant
• History of adverse effects to phototherapy
• Subject has single sided lesions
• Subject has immunosuppression
• Subject has radiation therapy to the study area
• Subject has topical or oral steroid use or chemotherapy within the last 6 months
• History of keloids or hypertrophic scar